Manteia

ENSMUSG00000029309

Mus musculus

Features

Gene ID:	ENSMUSG00000029309

Biological name :	Sparcl1

Synonyms :	P70663 / Sparcl1 / SPARC-like protein 1

Possible biological names infered from orthology :	Q14515 / SPARC like 1

Species:	Mus musculus

Chr. number:	5
Strand:	-1
Band:	E5
Gene start:	104079111
Gene end:	104113733

Corresponding Affymetrix probe sets:	10531931 (MoGene1.0st) 1416114_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000031249 Ensembl peptide - ENSMUSP00000143177 NCBI entrez gene - 13602 See in Manteia. MGI - MGI:108110 RefSeq - XM_017320656 RefSeq - NM_010097 RefSeq - XM_006534768 RefSeq Peptide - NP_001345945 RefSeq Peptide - NP_034227 RefSeq Peptide - NP_001345943 swissprot - P70663 swissprot - A0A0G2JFH7 Ensembl - ENSMUSG00000029309

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Sparc / P07214 / secreted acidic cysteine rich glycoprotein / P09486* / secreted protein acidic and cysteine rich*	ENSMUSG00000018593	24

Protein motifs (from Interpro)

Interpro ID	Name
IPR001999	Osteonectin-like, conserved site
IPR002048	EF-hand domain
IPR002350	Kazal domain
IPR003645	Follistatin-like, N-terminal
IPR011992	EF-hand domain pair
IPR015369	Follistatin/Osteonectin EGF domain
IPR016359	SPARC-like protein 1
IPR018247	EF-Hand 1, calcium-binding site
IPR019577	SPARC/Testican, calcium-binding domain
IPR036058	Kazal domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0048856	anatomical structure development	IBA
cellular_component	GO:0005576	extracellular region	ISO
cellular_component	GO:0005615	extracellular space	IBA
molecular_function	GO:0005509	calcium ion binding	IEA
molecular_function	GO:0005515	protein binding	IEA
molecular_function	GO:0005518	collagen binding	IEA
molecular_function	GO:0046872	metal ion binding	IEA
molecular_function	GO:0050840	extracellular matrix binding	IEA

Pathways (from Reactome)

Pathway description

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000877	abnormal Purkinje cell	"any structural anomaly of the neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex; these inhibitory neurons provide the output of the cerebellar cortex through axons that project into the white matter, and extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells" [J:46140, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Foxn1^tm1.1Dmsu/Foxn1^tm1.1Dmsu,Tg(KRT5-cre/ERT2)2Ipc/0 Genetic Background: involves: 129/Sv * C57BL/6 * SJL
MP:0002183	gliosis	"increased growth pattern of neuroglia in a damaged area of the brain or spinal cord" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Foxn1^tm1.1Dmsu/Foxn1^tm1.1Dmsu,Tg(KRT5-cre/ERT2)2Ipc/0 Genetic Background: involves: 129/Sv * C57BL/6 * SJL

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr