ENSG00000152818


Homo sapiens

Features
Gene ID: ENSG00000152818
  
Biological name :UTRN
  
Synonyms : P46939 / UTRN / utrophin
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q24.2
Gene start: 144285701
Gene end: 144853034
  
Corresponding Affymetrix probe sets: 213022_s_at (Human Genome U133 Plus 2.0 Array)   213023_at (Human Genome U133 Plus 2.0 Array)   225093_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000398923
Ensembl peptide - ENSP00000396276
Ensembl peptide - ENSP00000404205
Ensembl peptide - ENSP00000487153
Ensembl peptide - ENSP00000356494
Ensembl peptide - ENSP00000356495
Ensembl peptide - ENSP00000356496
Ensembl peptide - ENSP00000356515
Ensembl peptide - ENSP00000387927
Ensembl peptide - ENSP00000390879
NCBI entrez gene - 7402     See in Manteia.
OMIM - 128240
RefSeq - XM_017011245
RefSeq - XM_005267127
RefSeq - XM_005267130
RefSeq - XM_005267133
RefSeq - XM_006715560
RefSeq - XM_011536101
RefSeq - XM_011536102
RefSeq - XM_011536106
RefSeq - XM_011536107
RefSeq - XM_011536109
RefSeq - XM_017011243
RefSeq - XM_017011244
RefSeq - NM_007124
RefSeq Peptide - NP_009055
swissprot - H0Y337
swissprot - A0A0A0MSM3
swissprot - P46939
swissprot - Q5JT44
swissprot - Q5JT45
swissprot - Q5JT49
swissprot - Q5SYY2
swissprot - Q5T097
swissprot - A0A0D9SG57
swissprot - Q5T098
Ensembl - ENSG00000152818
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 utrnENSDARG00000100222Danio rerio
 UTRNENSGALG00000012256Gallus gallus
 UtrnENSMUSG00000019820Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DMD / P11532 / dystrophinENSG0000019894750
DRP2 / Q13474 / dystrophin related protein 2ENSG0000010238513
DTNB / O60941 / dystrobrevin betaENSG000001381015
DTNA / Q9Y4J8 / dystrobrevin alphaENSG000001347695
DYTN / A2CJ06 / dystrotelinENSG000002321254


Protein motifs (from Interpro)
Interpro ID Name
 IPR000433  Zinc finger, ZZ-type
 IPR001202  WW domain
 IPR001589  Actinin-type actin-binding domain, conserved site
 IPR001715  Calponin homology domain
 IPR002017  Spectrin repeat
 IPR011992  EF-hand domain pair
 IPR015153  EF-hand domain, type 1
 IPR015154  EF-hand domain, type 2
 IPR018159  Spectrin/alpha-actinin
 IPR035436  Dystrophin/utrophin
 IPR036020  WW domain superfamily
 IPR036872  CH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001954 positive regulation of cell-matrix adhesion IMP
 biological_processGO:0006936 muscle contraction TAS
 biological_processGO:0007517 muscle organ development TAS
 biological_processGO:0007528 neuromuscular junction development IEA
 biological_processGO:0014894 response to denervation involved in regulation of muscle adaptation IEA
 biological_processGO:2000649 regulation of sodium ion transmembrane transporter activity ISS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016010 dystrophin-associated glycoprotein complex IEA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030175 filopodium IDA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0030864 cortical actin cytoskeleton IEA
 cellular_componentGO:0031527 filopodium membrane IDA
 cellular_componentGO:0031594 neuromuscular junction IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0042383 sarcolemma IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0070938 contractile ring IDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005178 integrin binding IPI
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0017166 vinculin binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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