ENSG00000152904


Homo sapiens

Features
Gene ID: ENSG00000152904
  
Biological name :GGPS1
  
Synonyms : geranylgeranyl diphosphate synthase 1 / GGPS1 / O95749
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q42.3
Gene start: 235327350
Gene end: 235344532
  
Corresponding Affymetrix probe sets: 202321_at (Human Genome U133 Plus 2.0 Array)   202322_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417865
Ensembl peptide - ENSP00000351852
Ensembl peptide - ENSP00000418690
Ensembl peptide - ENSP00000375728
Ensembl peptide - ENSP00000417772
Ensembl peptide - ENSP00000282841
NCBI entrez gene - 9453     See in Manteia.
OMIM - 606982
RefSeq - NM_001037277
RefSeq Peptide - NP_001032354
swissprot - C9J7M1
swissprot - C9J6G3
swissprot - A0A024R3W4
swissprot - O95749
Ensembl - ENSG00000152904
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ggps1ENSDARG00000023627Danio rerio
 GGPS1ENSGALG00000042853Gallus gallus
 Ggps1ENSMUSG00000021302Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000092  Polyprenyl synthetase
 IPR008949  Isoprenoid synthase domain superfamily
 IPR033749  Polyprenyl synthetase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006695 cholesterol biosynthetic process TAS
 biological_processGO:0006720 isoprenoid metabolic process IDA
 biological_processGO:0008299 isoprenoid biosynthetic process IEA
 biological_processGO:0033384 geranyl diphosphate biosynthetic process IEA
 biological_processGO:0033386 geranylgeranyl diphosphate biosynthetic process IEA
 biological_processGO:0045337 farnesyl diphosphate biosynthetic process IEA
 biological_processGO:0045540 regulation of cholesterol biosynthetic process TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004161 dimethylallyltranstransferase activity TAS
 molecular_functionGO:0004311 farnesyltranstransferase activity IEA
 molecular_functionGO:0004337 geranyltranstransferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Cholesterol biosynthesis
Activation of gene expression by SREBF (SREBP)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000152904 GGPS1 / O95749 / geranylgeranyl diphosphate synthase 1  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr