ENSG00000153266


Homo sapiens

Features
Gene ID: ENSG00000153266
  
Biological name :FEZF2
  
Synonyms : FEZF2 / FEZ family zinc finger 2 / Q8TBJ5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p14.2
Gene start: 62369681
Gene end: 62374324
  
Corresponding Affymetrix probe sets: 221086_s_at (Human Genome U133 Plus 2.0 Array)   233897_at (Human Genome U133 Plus 2.0 Array)   233972_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000283268
Ensembl peptide - ENSP00000418804
Ensembl peptide - ENSP00000418589
NCBI entrez gene - 55079     See in Manteia.
OMIM - 607414
RefSeq - NM_018008
RefSeq Peptide - NP_060478
swissprot - A0A140VKG3
swissprot - Q8TBJ5
Ensembl - ENSG00000153266
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fezf2ENSDARG00000070677Danio rerio
 FEZF2ENSGALG00000007184Gallus gallus
 Fezf2ENSMUSG00000021743Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FEZF1 / A0PJY2 / FEZ family zinc finger 1ENSG0000012861055
ZNF8 / P17098 / zinc finger protein 8ENSG0000027812925
GFI1 / Q99684 / growth factor independent 1 transcriptional repressorENSG0000016267623
GFI1B / Q5VTD9 / growth factor independent 1B transcriptional repressorENSG0000016570222


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0007413 axonal fasciculation IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0016358 dendrite development IEA
 biological_processGO:0021537 telencephalon development IEA
 biological_processGO:0021542 dentate gyrus development IEA
 biological_processGO:0021797 forebrain anterior/posterior pattern specification IEA
 biological_processGO:0021853 cerebral cortex GABAergic interneuron migration IEA
 biological_processGO:0021895 cerebral cortex neuron differentiation IEA
 biological_processGO:0021902 commitment of neuronal cell to specific neuron type in forebrain IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0043697 cell dedifferentiation IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0045666 positive regulation of neuron differentiation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0048664 neuron fate determination IEA
 biological_processGO:0050767 regulation of neurogenesis IEA
 biological_processGO:1902667 regulation of axon guidance IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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