ENSG00000153291


Homo sapiens

Features
Gene ID: ENSG00000153291
  
Biological name :SLC25A27
  
Synonyms : O95847 / SLC25A27 / solute carrier family 25 member 27
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p12.3
Gene start: 46652915
Gene end: 46678193
  
Corresponding Affymetrix probe sets: 1552774_a_at (Human Genome U133 Plus 2.0 Array)   1554161_at (Human Genome U133 Plus 2.0 Array)   229361_at (Human Genome U133 Plus 2.0 Array)   230624_at (Human Genome U133 Plus 2.0 Array)   231787_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000474828
Ensembl peptide - ENSP00000360398
Ensembl peptide - ENSP00000412024
Ensembl peptide - ENSP00000474429
Ensembl peptide - ENSP00000474781
Ensembl peptide - ENSP00000473804
NCBI entrez gene - 9481     See in Manteia.
OMIM - 613725
RefSeq - XM_017011512
RefSeq - NM_001204051
RefSeq - NM_001204052
RefSeq - NM_004277
RefSeq - XM_005249483
RefSeq Peptide - NP_004268
RefSeq Peptide - NP_001190980
RefSeq Peptide - NP_001190981
swissprot - S4R3J2
swissprot - S4R300
swissprot - O95847
swissprot - Q5VTS8
Ensembl - ENSG00000153291
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc25a27ENSDARG00000042873Danio rerio
 Slc25a27ENSMUSG00000023912Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O95258 / SLC25A14 / solute carrier family 25 member 14ENSG0000010207835
Q5SVS4 / SLC25A30 / solute carrier family 25 member 30ENSG0000017403234
UCP3 / P55916 / uncoupling protein 3ENSG0000017556433
UCP2 / P55851 / uncoupling protein 2ENSG0000017556731
UCP1 / P25874 / uncoupling protein 1ENSG0000010942428
Q02978 / SLC25A11 / solute carrier family 25 member 11ENSG0000010852828
AC139530.2ENSG0000026266027
Q9UBX3 / SLC25A10 / solute carrier family 25 member 10ENSG0000018304821


Protein motifs (from Interpro)
Interpro ID Name
 IPR018108  Mitochondrial substrate/solute carrier
 IPR023395  Mitochondrial carrier domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006839 mitochondrial transport IBA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0009409 response to cold IBA
 biological_processGO:0010917 negative regulation of mitochondrial membrane potential IEA
 biological_processGO:0035356 cellular triglyceride homeostasis IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0046324 regulation of glucose import IEA
 biological_processGO:0048839 inner ear development IEA
 biological_processGO:0051562 negative regulation of mitochondrial calcium ion concentration IEA
 biological_processGO:0051881 regulation of mitochondrial membrane potential IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070997 neuron death IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0031966 mitochondrial membrane IDA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0045177 apical part of cell IEA
 molecular_functionGO:0022857 transmembrane transporter activity IBA


Pathways (from Reactome)
Pathway description
The fatty acid cycling model
The proton buffering model


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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