ENSG00000154174


Homo sapiens

Features
Gene ID: ENSG00000154174
  
Biological name :TOMM70
  
Synonyms : O94826 / TOMM70 / translocase of outer mitochondrial membrane 70
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q12.2
Gene start: 100363431
Gene end: 100401398
  
Corresponding Affymetrix probe sets: 201512_s_at (Human Genome U133 Plus 2.0 Array)   201519_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000284320
NCBI entrez gene - 9868     See in Manteia.
OMIM - 606081
RefSeq - NM_014820
RefSeq Peptide - NP_055635
swissprot - O94826
Ensembl - ENSG00000154174
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tomm70aENSDARG00000029639Danio rerio
 TOMM70ENSGALG00000015285Gallus gallus
 Q9CZW5ENSMUSG00000022752Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SPAG1 / Q07617 / sperm associated antigen 1ENSG0000010445018
RPAP3 / Q9H6T3 / RNA polymerase II associated protein 3ENSG0000000517516
Q9H3U1 / UNC45A / unc-45 myosin chaperone AENSG0000014055314
Q8IWX7 / UNC45B / unc-45 myosin chaperone BENSG0000014116113
Q15785 / TOMM34 / translocase of outer mitochondrial membrane 34ENSG0000002577211
TTC1 / Q99614 / tetratricopeptide repeat domain 1ENSG000001133129


Protein motifs (from Interpro)
Interpro ID Name
 IPR001440  Tetratricopeptide repeat 1
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006626 protein targeting to mitochondrion TAS
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0071806 protein transmembrane transport IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane TAS
 cellular_componentGO:0005742 mitochondrial outer membrane translocase complex TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008320 protein transmembrane transporter activity TAS


Pathways (from Reactome)
Pathway description
Mitochondrial protein import
Pink/Parkin Mediated Mitophagy
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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