ENSG00000140553


Homo sapiens

Features
Gene ID: ENSG00000140553
  
Biological name :UNC45A
  
Synonyms : Q9H3U1 / UNC45A / unc-45 myosin chaperone A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q26.1
Gene start: 90930180
Gene end: 90954093
  
Corresponding Affymetrix probe sets: 207499_x_at (Human Genome U133 Plus 2.0 Array)   221708_s_at (Human Genome U133 Plus 2.0 Array)   231290_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000377816
Ensembl peptide - ENSP00000407487
Ensembl peptide - ENSP00000491150
NCBI entrez gene - 55898     See in Manteia.
OMIM - 611219
RefSeq - NM_018671
RefSeq - XM_017022407
RefSeq - NM_001039675
RefSeq - NM_001323619
RefSeq - NM_001323620
RefSeq - NM_001323621
RefSeq - XM_005254963
RefSeq - XM_011521779
RefSeq - XM_011521780
RefSeq Peptide - NP_001310548
RefSeq Peptide - NP_001310549
RefSeq Peptide - NP_061141
RefSeq Peptide - NP_001310550
RefSeq Peptide - NP_001034764
swissprot - A0A1W2PNX8
swissprot - Q9H3U1
Ensembl - ENSG00000140553
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 unc45aENSDARG00000103643Danio rerio
 UNC45AENSGALG00000029714Gallus gallus
 Q99KD5ENSMUSG00000030533Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8IWX7 / UNC45B / unc-45 myosin chaperone BENSG0000014116156
RPAP3 / Q9H6T3 / RNA polymerase II associated protein 3ENSG0000000517511
SPAG1 / Q07617 / sperm associated antigen 1ENSG0000010445010
O94826 / TOMM70 / translocase of outer mitochondrial membrane 70ENSG000001541749
TTC1 / Q99614 / tetratricopeptide repeat domain 1ENSG000001133126
Q15785 / TOMM34 / translocase of outer mitochondrial membrane 34ENSG000000257726


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR016024  Armadillo-type fold
 IPR019734  Tetratricopeptide repeat
 IPR024660  UNC-45/Cro1/She4, central domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007517 muscle organ development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0061077 chaperone-mediated protein folding IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0051879 Hsp90 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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