ENSDARG00000103643


Danio rerio

Features
Gene ID: ENSDARG00000103643
  
Biological name :unc45a
  
Synonyms : unc45a / unc-45 myosin chaperone A
  
Possible biological names infered from orthology : Q99KD5 / Q9H3U1
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 8627748
Gene end: 8660729
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000137669
Ensembl peptide - ENSDARP00000140505
Ensembl peptide - ENSDARP00000132911
Ensembl peptide - ENSDARP00000136856
NCBI entrez gene - 550364     See in Manteia.
RefSeq - NM_001017671
RefSeq Peptide - NP_001017671
swissprot - A0A0R4IU52
swissprot - F1QU23
swissprot - Q567I0
ZFIN ID - ZDB-GENE-050417-158
Ensembl - ENSDARG00000103643
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 UNC45AENSGALG00000029714Gallus gallus
 Q9H3U1ENSG00000140553Homo sapiens
 Q99KD5ENSMUSG00000030533Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6DGE9 / unc45b / unc-45 myosin chaperone B / Q8CGY6* / Q8IWX7*ENSDARG0000000843354
rpap3 / RNA polymerase II associated protein 3 / Q9H6T3*ENSDARG000000879629
tomm70a / translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) / Q9CZW5* / TOMM70* / O94826* / Mitochondrial import receptor subunit TOM70 * / translocase of outer mitoc...ENSDARG000000296398
spag1a / F1RBN2 / sperm associated antigen 1a / SPAG1* / Q07617* / sperm associated antigen 1*ENSDARG000000040177
tomm34 / translocase of outer mitochondrial membrane 34 / Q15785*ENSDARG000000015577
ttc1 / tetratricopeptide repeat domain 1 / Q91Z38* / Q99614*ENSDARG000000445675
spag1b / sperm associated antigen 1bENSDARG000000694993


Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR011989  Armadillo-like helical
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR016024  Armadillo-type fold
 IPR019734  Tetratricopeptide repeat
 IPR024660  UNC-45/Cro1/She4, central domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0008015 blood circulation IMP
 biological_processGO:0048514 blood vessel morphogenesis IMP
 biological_processGO:0051216 cartilage development IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood quality , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000076 swim bladder swim bladder aplastic , abnormal
Show

 ZFA:0000170 basibranchial basibranchial condensed , abnormal
Show

 ZFA:0000407 pectoral girdle pectoral girdle aplastic/hypoplastic , abnormal
Show

 ZFA:0000604 ventral aorta ventral aorta morphology , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism viability , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage shortened , abnormal
Show

 ZFA:0001272 palatoquadrate arch palatoquadrate arch decreased length , abnormal
Show

 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage shortened , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage orientation ceratohyal cartilage , abnormal
Show

 ZFA:0001439 anatomical system anatomical system quality , abnormal
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 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage orientation ceratobranchial cartilage , abnormal
ceratobranchial cartilage decreased distance ceratobranchial cartilage , abnormal
ceratobranchial cartilage dislocated ceratobranchial cartilage , abnormal
Show

 ZFA:0001651 sternohyoid sternohyoid displaced , abnormal
Show

 ZFA:0005003 pharyngeal vasculature pharyngeal vasculature morphology , abnormal
Show

 ZFA:0005009 aortic arch 5 aortic arch 5 unlumenized , abnormal
Show

 ZFA:0005016 aortic arch 6 aortic arch 6 unlumenized , abnormal
Show

 ZFA:0005026 primary head sinus primary head sinus morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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