ENSG00000156234


Homo sapiens

Features
Gene ID: ENSG00000156234
  
Biological name :CXCL13
  
Synonyms : CXCL13 / C-X-C motif chemokine ligand 13 / O43927
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q21.1
Gene start: 77511753
Gene end: 77611834
  
Corresponding Affymetrix probe sets: 205242_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000286758
NCBI entrez gene - 10563     See in Manteia.
OMIM - 605149
RefSeq - XM_006714063
RefSeq - NM_006419
RefSeq Peptide - NP_006410
swissprot - O43927
swissprot - Q53X90
Ensembl - ENSG00000156234
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Cxcl13ENSMUSG00000023078Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001089  CXC chemokine
 IPR001811  Chemokine interleukin-8-like domain
 IPR018048  CXC chemokine, conserved site
 IPR033899  CXC Chemokine domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002467 germinal center formation NAS
 biological_processGO:0002518 lymphocyte chemotaxis across high endothelial venule ISS
 biological_processGO:0002544 chronic inflammatory response NAS
 biological_processGO:0002920 regulation of humoral immune response NAS
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006952 defense response IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IC
 biological_processGO:0007166 cell surface receptor signaling pathway IDA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IDA
 biological_processGO:0007267 cell-cell signaling IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010820 positive regulation of T cell chemotaxis IDA
 biological_processGO:0032496 response to lipopolysaccharide IBA
 biological_processGO:0033625 positive regulation of integrin activation ISS
 biological_processGO:0033634 positive regulation of cell-cell adhesion mediated by integrin ISS
 biological_processGO:0035754 B cell chemotaxis IDA
 biological_processGO:0035768 endothelial cell chemotaxis to fibroblast growth factor IDA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0042742 defense response to bacterium IDA
 biological_processGO:0045765 regulation of angiogenesis NAS
 biological_processGO:0060326 cell chemotaxis IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0090630 activation of GTPase activity ISS
 biological_processGO:2000545 negative regulation of endothelial cell chemotaxis to fibroblast growth factor IDA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005623 cell IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0008009 chemokine activity IDA
 molecular_functionGO:0008201 heparin binding IDA
 molecular_functionGO:0017134 fibroblast growth factor binding IDA
 molecular_functionGO:0031724 CXCR5 chemokine receptor binding IDA
 molecular_functionGO:0031735 CCR10 chemokine receptor binding IDA
 molecular_functionGO:0046982 protein heterodimerization activity IDA
 molecular_functionGO:0048018 receptor ligand activity IDA
 molecular_functionGO:0048248 CXCR3 chemokine receptor binding IPI


Pathways (from Reactome)
Pathway description
Chemokine receptors bind chemokines
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000160683 CXCR5 / P32302 / C-X-C motif chemokine receptor 5  / complex / reaction






 

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