ENSG00000160683


Homo sapiens

Features
Gene ID: ENSG00000160683
  
Biological name :CXCR5
  
Synonyms : C-X-C motif chemokine receptor 5 / CXCR5 / P32302
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q23.3
Gene start: 118883766
Gene end: 118897799
  
Corresponding Affymetrix probe sets: 206126_at (Human Genome U133 Plus 2.0 Array)   216734_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000292174
NCBI entrez gene - 643     See in Manteia.
OMIM - 601613
RefSeq - NM_001716
RefSeq Peptide - NP_001707
swissprot - A0N0R2
swissprot - P32302
Ensembl - ENSG00000160683
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cxcr5ENSDARG00000010514Danio rerio
 CXCR5ENSGALG00000007675Gallus gallus
 Cxcr5ENSMUSG00000047880Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CXCR3 / P49682 / C-X-C motif chemokine receptor 3ENSG0000018681037
CXCR2 / P25025 / C-X-C motif chemokine receptor 2ENSG0000018087134
CCR10 / P46092 / C-C motif chemokine receptor 10ENSG0000018445132
CXCR1 / P25024 / C-X-C motif chemokine receptor 1ENSG0000016346432
CCR7 / P32248 / C-C motif chemokine receptor 7ENSG0000012635331
CXCR4 / P61073 / C-X-C motif chemokine receptor 4ENSG0000012196630
CCR9 / P51686 / C-C motif chemokine receptor 9ENSG0000017358529
ACKR2 / O00590 / atypical chemokine receptor 2ENSG0000014464828
CCR6 / P51684 / C-C motif chemokine receptor 6ENSG0000011248628
CCR4 / P51679 / C-C motif chemokine receptor 4ENSG0000018381328
CX3CR1 / P49238 / C-X3-C motif chemokine receptor 1ENSG0000016832926
CCR1 / P32246 / C-C motif chemokine receptor 1ENSG0000016382326
CCR3 / P51677 / C-C motif chemokine receptor 3ENSG0000018362526
ACKR4 / Q9NPB9 / atypical chemokine receptor 4ENSG0000012904826
CCR2 / P41597 / C-C motif chemokine receptor 2ENSG0000012180726
CXCR6 / O00574 / C-X-C motif chemokine receptor 6ENSG0000017221525
CCR5 / P51681 / C-C motif chemokine receptor 5 (gene/pseudogene)ENSG0000016079125
CCR8 / P51685 / C-C motif chemokine receptor 8ENSG0000017993425
XCR1 / P46094 / X-C motif chemokine receptor 1ENSG0000017357825


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001053  CXC chemokine receptor 5
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0030595 leukocyte chemotaxis IEA
 biological_processGO:0032467 positive regulation of cytokinesis IMP
 biological_processGO:0042113 B cell activation IEA
 biological_processGO:0048535 lymph node development IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016494 C-X-C chemokine receptor activity IEA


Pathways (from Reactome)
Pathway description
Chemokine receptors bind chemokines
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000156234 CXCL13 / O43927 / C-X-C motif chemokine ligand 13  / complex / reaction






 

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