ENSG00000184451


Homo sapiens

Features
Gene ID: ENSG00000184451
  
Biological name :CCR10
  
Synonyms : C-C motif chemokine receptor 10 / CCR10 / P46092
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.2
Gene start: 42678889
Gene end: 42683917
  
Corresponding Affymetrix probe sets: 220565_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467331
Ensembl peptide - ENSP00000468135
Ensembl peptide - ENSP00000332504
NCBI entrez gene - 2826     See in Manteia.
OMIM - 600240
RefSeq - NM_016602
RefSeq Peptide - NP_057686
swissprot - P46092
swissprot - K7EPC9
swissprot - K7ER70
Ensembl - ENSG00000184451
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CCR10ENSGALG00000028519Gallus gallus
 Ccr10ENSMUSG00000044052Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CXCR3 / P49682 / C-X-C motif chemokine receptor 3ENSG0000018681038
CCR7 / P32248 / C-C motif chemokine receptor 7ENSG0000012635336
CXCR5 / P32302 / C-X-C motif chemokine receptor 5ENSG0000016068333
CXCR2 / P25025 / C-X-C motif chemokine receptor 2ENSG0000018087132
ACKR2 / O00590 / atypical chemokine receptor 2ENSG0000014464831
CXCR1 / P25024 / C-X-C motif chemokine receptor 1ENSG0000016346431
CCR6 / P51684 / C-C motif chemokine receptor 6ENSG0000011248631
ACKR4 / Q9NPB9 / atypical chemokine receptor 4ENSG0000012904831
CCR9 / P51686 / C-C motif chemokine receptor 9ENSG0000017358530
CCR3 / P51677 / C-C motif chemokine receptor 3ENSG0000018362529
CCR1 / P32246 / C-C motif chemokine receptor 1ENSG0000016382329
CCR5 / P51681 / C-C motif chemokine receptor 5 (gene/pseudogene)ENSG0000016079128
CCR4 / P51679 / C-C motif chemokine receptor 4ENSG0000018381328
CX3CR1 / P49238 / C-X3-C motif chemokine receptor 1ENSG0000016832928
CXCR4 / P61073 / C-X-C motif chemokine receptor 4ENSG0000012196627
CCR2 / P41597 / C-C motif chemokine receptor 2ENSG0000012180726
CXCR6 / O00574 / C-X-C motif chemokine receptor 6ENSG0000017221526
XCR1 / P46094 / X-C motif chemokine receptor 1ENSG0000017357825
CCR8 / P51685 / C-C motif chemokine receptor 8ENSG0000017993423


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000355  Chemokine receptor family
 IPR005382  CC chemokine receptor 10
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004950 chemokine receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016493 C-C chemokine receptor activity IEA


Pathways (from Reactome)
Pathway description
Chemokine receptors bind chemokines
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000151882 CCL28 / Q9NRJ3 / C-C motif chemokine ligand 28  / complex / reaction
 ENSG00000213927 CCL27 / Q9Y4X3 / C-C motif chemokine ligand 27  / complex / reaction






 

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