ENSG00000172215


Homo sapiens

Features
Gene ID: ENSG00000172215
  
Biological name :CXCR6
  
Synonyms : C-X-C motif chemokine receptor 6 / CXCR6 / O00574
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p21.31
Gene start: 45940933
Gene end: 45948353
  
Corresponding Affymetrix probe sets: 206974_at (Human Genome U133 Plus 2.0 Array)   211469_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000395704
Ensembl peptide - ENSP00000396886
Ensembl peptide - ENSP00000396218
Ensembl peptide - ENSP00000304414
NCBI entrez gene - 10663     See in Manteia.
OMIM - 605163
RefSeq - XM_011533290
RefSeq - XM_011533291
RefSeq - NM_006564
RefSeq - XM_005264809
RefSeq Peptide - NP_006555
swissprot - O00574
swissprot - A0N0N3
Ensembl - ENSG00000172215
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Cxcr6ENSMUSG00000048521Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCR6 / P51684 / C-C motif chemokine receptor 6ENSG0000011248635
CCR7 / P32248 / C-C motif chemokine receptor 7ENSG0000012635335
CCR9 / P51686 / C-C motif chemokine receptor 9ENSG0000017358534
ACKR4 / Q9NPB9 / atypical chemokine receptor 4ENSG0000012904833
CCR5 / P51681 / C-C motif chemokine receptor 5 (gene/pseudogene)ENSG0000016079131
CX3CR1 / P49238 / C-X3-C motif chemokine receptor 1ENSG0000016832931
CCR1 / P32246 / C-C motif chemokine receptor 1ENSG0000016382330
CCR2 / P41597 / C-C motif chemokine receptor 2ENSG0000012180730
CXCR4 / P61073 / C-X-C motif chemokine receptor 4ENSG0000012196630
CXCR2 / P25025 / C-X-C motif chemokine receptor 2ENSG0000018087130
CCR3 / P51677 / C-C motif chemokine receptor 3ENSG0000018362530
CXCR1 / P25024 / C-X-C motif chemokine receptor 1ENSG0000016346429
CXCR3 / P49682 / C-X-C motif chemokine receptor 3ENSG0000018681029
CCR4 / P51679 / C-C motif chemokine receptor 4ENSG0000018381329
CCR8 / P51685 / C-C motif chemokine receptor 8ENSG0000017993428
CCR10 / P46092 / C-C motif chemokine receptor 10ENSG0000018445127
CXCR5 / P32302 / C-X-C motif chemokine receptor 5ENSG0000016068327
ACKR2 / O00590 / atypical chemokine receptor 2ENSG0000014464827
XCR1 / P46094 / X-C motif chemokine receptor 1ENSG0000017357827


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000355  Chemokine receptor family
 IPR002235  CXC chemokine receptor 6
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0019079 viral genome replication TAS
 biological_processGO:0070098 chemokine-mediated signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0004950 chemokine receptor activity IEA
 molecular_functionGO:0015026 coreceptor activity TAS
 molecular_functionGO:0016494 C-X-C chemokine receptor activity IEA
 molecular_functionGO:0019958 C-X-C chemokine binding IEA


Pathways (from Reactome)
Pathway description
Chemokine receptors bind chemokines
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000161921 CXCL16 / Q9H2A7 / C-X-C motif chemokine ligand 16  / reaction / complex






 

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