ENSG00000183625


Homo sapiens

Features
Gene ID: ENSG00000183625
  
Biological name :CCR3
  
Synonyms : C-C motif chemokine receptor 3 / CCR3 / P51677
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p21.31
Gene start: 46163604
Gene end: 46266706
  
Corresponding Affymetrix probe sets: 208304_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000401822
Ensembl peptide - ENSP00000389336
Ensembl peptide - ENSP00000441600
Ensembl peptide - ENSP00000350003
Ensembl peptide - ENSP00000379271
Ensembl peptide - ENSP00000379273
NCBI entrez gene - 1232     See in Manteia.
OMIM - 601268
RefSeq - XM_017005686
RefSeq - NM_001164680
RefSeq - NM_001837
RefSeq - NM_178328
RefSeq - NM_178329
RefSeq - XM_006712960
RefSeq - XM_011533335
RefSeq - XM_017005685
RefSeq Peptide - NP_847899
RefSeq Peptide - NP_001158152
RefSeq Peptide - NP_001828
RefSeq Peptide - NP_847898
swissprot - A0A024R2Z3
swissprot - P51677
swissprot - Q8TDP4
swissprot - Q8TDP5
Ensembl - ENSG00000183625
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ccr11.1ENSDARG00000070755Danio rerio
 ccr2ENSDARG00000105363Danio rerio
 ccr2ENSDARG00000079829Danio rerio
 CCR2ENSGALG00000011733Gallus gallus
 CCR5ENSGALG00000037077Gallus gallus
 Ccr3ENSMUSG00000035448Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCR1 / P32246 / C-C motif chemokine receptor 1ENSG0000016382359
CCR5 / P51681 / C-C motif chemokine receptor 5 (gene/pseudogene)ENSG0000016079147
CCR2 / P41597 / C-C motif chemokine receptor 2ENSG0000012180745
CCR4 / P51679 / C-C motif chemokine receptor 4ENSG0000018381341
CX3CR1 / P49238 / C-X3-C motif chemokine receptor 1ENSG0000016832937
CCR8 / P51685 / C-C motif chemokine receptor 8ENSG0000017993434
ACKR2 / O00590 / atypical chemokine receptor 2ENSG0000014464833
CCR6 / P51684 / C-C motif chemokine receptor 6ENSG0000011248631
CCR7 / P32248 / C-C motif chemokine receptor 7ENSG0000012635331
CCR9 / P51686 / C-C motif chemokine receptor 9ENSG0000017358530
XCR1 / P46094 / X-C motif chemokine receptor 1ENSG0000017357829
CXCR3 / P49682 / C-X-C motif chemokine receptor 3ENSG0000018681029
CCR10 / P46092 / C-C motif chemokine receptor 10ENSG0000018445128
CXCR2 / P25025 / C-X-C motif chemokine receptor 2ENSG0000018087128
CXCR6 / O00574 / C-X-C motif chemokine receptor 6ENSG0000017221527
CXCR1 / P25024 / C-X-C motif chemokine receptor 1ENSG0000016346427
CXCR4 / P61073 / C-X-C motif chemokine receptor 4ENSG0000012196626
CXCR5 / P32302 / C-X-C motif chemokine receptor 5ENSG0000016068326
ACKR4 / Q9NPB9 / atypical chemokine receptor 4ENSG0000012904826


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000355  Chemokine receptor family
 IPR002238  CC chemokine receptor 3
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IEA
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0006968 cellular defense response TAS
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004950 chemokine receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016493 C-C chemokine receptor activity IEA
 molecular_functionGO:0019957 C-C chemokine binding IDA


Pathways (from Reactome)
Pathway description
Chemokine receptors bind chemokines
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000181374 CCL13 / Q99616 / C-C motif chemokine ligand 13  / complex / reaction
 ENSG00000271503 CCL5 / P13501 / C-C motif chemokine ligand 5  / complex / reaction






 

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