ENSG00000156671


Homo sapiens

Features
Gene ID: ENSG00000156671
  
Biological name :SAMD8
  
Synonyms : Q96LT4 / SAMD8 / sterile alpha motif domain containing 8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q22.2
Gene start: 75099586
Gene end: 75182123
  
Corresponding Affymetrix probe sets: 225950_at (Human Genome U133 Plus 2.0 Array)   242062_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000438042
Ensembl peptide - ENSP00000361772
Ensembl peptide - ENSP00000361775
Ensembl peptide - ENSP00000391799
NCBI entrez gene - 142891     See in Manteia.
OMIM - 611575
RefSeq - XM_017015739
RefSeq - NM_001174156
RefSeq - NM_144660
RefSeq - XM_005269541
RefSeq - XM_011539311
RefSeq - XM_011539312
RefSeq - XM_017015738
RefSeq Peptide - NP_001167627
RefSeq Peptide - NP_653261
swissprot - V9HVY4
swissprot - A0A0A0MRR2
swissprot - Q5JSC9
swissprot - Q96LT4
Ensembl - ENSG00000156671
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SAMD8ENSDARG00000074663Danio rerio
 SAMD8ENSGALG00000005004Gallus gallus
 Samd8ENSMUSG00000021770Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SGMS1 / sphingomyelin synthase 1ENSG0000019896435
SGMS2 / Q8NHU3 / sphingomyelin synthase 2ENSG0000016402332


Protein motifs (from Interpro)
Interpro ID Name
 IPR001660  Sterile alpha motif domain
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR025749  Sphingomyelin synthase-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006665 sphingolipid metabolic process IEA
 biological_processGO:0006686 sphingomyelin biosynthetic process NAS
 biological_processGO:0030148 sphingolipid biosynthetic process TAS
 biological_processGO:0046513 ceramide biosynthetic process IEA
 biological_processGO:1905373 ceramide phosphoethanolamine biosynthetic process IEA
 biological_processGO:2000303 regulation of ceramide biosynthetic process IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 cellular_componentGO:0030173 integral component of Golgi membrane IBA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IDA
 molecular_functionGO:0002950 ceramide phosphoethanolamine synthase activity TAS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0033188 sphingomyelin synthase activity IBA
 molecular_functionGO:0047493 ceramide cholinephosphotransferase activity IBA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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