ENSG00000157064


Homo sapiens

Features
Gene ID: ENSG00000157064
  
Biological name :NMNAT2
  
Synonyms : nicotinamide nucleotide adenylyltransferase 2 / NMNAT2 / Q9BZQ4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q25.3
Gene start: 183248237
Gene end: 183418602
  
Corresponding Affymetrix probe sets: 1552712_a_at (Human Genome U133 Plus 2.0 Array)   1556029_s_at (Human Genome U133 Plus 2.0 Array)   1562818_at (Human Genome U133 Plus 2.0 Array)   209755_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000287713
Ensembl peptide - ENSP00000294868
NCBI entrez gene - 23057     See in Manteia.
OMIM - 608701
RefSeq - NM_015039
RefSeq - NM_170706
RefSeq Peptide - NP_055854
RefSeq Peptide - NP_733820
swissprot - Q9BZQ4
Ensembl - ENSG00000157064
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nmnat2ENSDARG00000004580Danio rerio
 NMNAT2ENSGALG00000004642Gallus gallus
 Nmnat2ENSMUSG00000042751Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NMNAT3 / Q96T66 / nicotinamide nucleotide adenylyltransferase 3ENSG0000016386432
NMNAT1 / Q9HAN9 / nicotinamide nucleotide adenylyltransferase 1ENSG0000017361432


Protein motifs (from Interpro)
Interpro ID Name
 IPR004821  Cytidyltransferase-like domain
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0009435 NAD biosynthetic process IEA
 biological_processGO:0019363 pyridine nucleotide biosynthetic process IEA
 biological_processGO:0019674 NAD metabolic process TAS
 biological_processGO:0034628 "de novo" NAD biosynthetic process from aspartate IBA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000309 nicotinamide-nucleotide adenylyltransferase activity TAS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004515 nicotinate-nucleotide adenylyltransferase activity EXP
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA


Pathways (from Reactome)
Pathway description
Nicotinate metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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