ENSG00000163864


Homo sapiens

Features
Gene ID: ENSG00000163864
  
Biological name :NMNAT3
  
Synonyms : nicotinamide nucleotide adenylyltransferase 3 / NMNAT3 / Q96T66
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q23
Gene start: 139560180
Gene end: 139678017
  
Corresponding Affymetrix probe sets: 228090_at (Human Genome U133 Plus 2.0 Array)   243738_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000494285
Ensembl peptide - ENSP00000427634
Ensembl peptide - ENSP00000494580
Ensembl peptide - ENSP00000496136
Ensembl peptide - ENSP00000496061
Ensembl peptide - ENSP00000495140
Ensembl peptide - ENSP00000495112
Ensembl peptide - ENSP00000296202
Ensembl peptide - ENSP00000340523
Ensembl peptide - ENSP00000412953
Ensembl peptide - ENSP00000423335
Ensembl peptide - ENSP00000425041
Ensembl peptide - ENSP00000426357
Ensembl peptide - ENSP00000426375
NCBI entrez gene - 349565     See in Manteia.
OMIM - 608702
RefSeq - XM_017006344
RefSeq - XM_017006332
RefSeq - XM_017006333
RefSeq - XM_017006334
RefSeq - XM_017006335
RefSeq - XM_017006336
RefSeq - XM_017006337
RefSeq - XM_017006338
RefSeq - XM_017006339
RefSeq - XM_017006340
RefSeq - XM_017006341
RefSeq - XM_017006342
RefSeq - XM_017006343
RefSeq - NM_001200047
RefSeq - NM_001320510
RefSeq - NM_001320511
RefSeq - NM_001320512
RefSeq - NM_001320513
RefSeq - NM_178177
RefSeq - XM_011512790
RefSeq - XM_011512791
RefSeq - XM_017006328
RefSeq - XM_017006329
RefSeq - XM_017006330
RefSeq - XM_017006331
RefSeq Peptide - NP_001307439
RefSeq Peptide - NP_001307440
RefSeq Peptide - NP_001307441
RefSeq Peptide - NP_001307442
RefSeq Peptide - NP_835471
RefSeq Peptide - NP_001186976
swissprot - D6R975
swissprot - D6RGH7
swissprot - D6RGG8
swissprot - D6REC8
swissprot - D6RHV4
swissprot - Q96T66
Ensembl - ENSG00000163864
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NMNAT3ENSDARG00000077034Danio rerio
 NMNAT3ENSGALG00000026187Gallus gallus
 Nmnat3ENSMUSG00000032456Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NMNAT1 / Q9HAN9 / nicotinamide nucleotide adenylyltransferase 1ENSG0000017361448
NMNAT2 / Q9BZQ4 / nicotinamide nucleotide adenylyltransferase 2ENSG0000015706438


Protein motifs (from Interpro)
Interpro ID Name
 IPR004821  Cytidyltransferase-like domain
 IPR005248  Nicotinate/nicotinamide nucleotide adenylyltransferase
 IPR005636  DTW
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0009435 NAD biosynthetic process IC
 biological_processGO:0009611 response to wounding IEA
 biological_processGO:0019363 pyridine nucleotide biosynthetic process IEA
 biological_processGO:0019674 NAD metabolic process TAS
 biological_processGO:0034628 "de novo" NAD biosynthetic process from aspartate IBA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000309 nicotinamide-nucleotide adenylyltransferase activity IBA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004515 nicotinate-nucleotide adenylyltransferase activity TAS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA


Pathways (from Reactome)
Pathway description
Nicotinate metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000163864 NMNAT3 / Q96T66 / nicotinamide nucleotide adenylyltransferase 3  / complex






 

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