ENSG00000157107


Homo sapiens

Features
Gene ID: ENSG00000157107
  
Biological name :FCHO2
  
Synonyms : FCH domain only 2 / FCHO2 / Q0JRZ9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q13.2
Gene start: 72955981
Gene end: 73090522
  
Corresponding Affymetrix probe sets: 1555153_s_at (Human Genome U133 Plus 2.0 Array)   228220_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000287761
Ensembl peptide - ENSP00000393776
Ensembl peptide - ENSP00000426842
Ensembl peptide - ENSP00000427296
NCBI entrez gene - 115548     See in Manteia.
OMIM - 613438
RefSeq - XM_017009023
RefSeq - XM_017009018
RefSeq - XM_017009019
RefSeq - XM_017009020
RefSeq - XM_017009021
RefSeq - XM_017009022
RefSeq - NM_001146032
RefSeq - NM_138782
RefSeq - XM_017009016
RefSeq - XM_017009017
RefSeq Peptide - NP_001139504
RefSeq Peptide - NP_620137
swissprot - H7BXJ4
swissprot - Q0JRZ9
swissprot - H0YAE2
Ensembl - ENSG00000157107
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000044064Gallus gallus
 ENSGALG00000015019Gallus gallus
 Fcho2ENSMUSG00000041685Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FCHO1 / O14526 / FCH domain only 1ENSG0000013047542
SGIP1 / Q9BQI5 / SH3 domain GRB2 like endophilin interacting protein 1ENSG0000011847337


Protein motifs (from Interpro)
Interpro ID Name
 IPR001060  FCH domain
 IPR018808  Muniscin C-terminal
 IPR027267  AH/BAR domain superfamily
 IPR028565  Mu homology domain
 IPR030122  F-BAR domain only protein 2
 IPR031160  F-BAR domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0010324 membrane invagination ISS
 biological_processGO:0048268 clathrin coat assembly IMP
 biological_processGO:0048488 synaptic vesicle endocytosis IEA
 biological_processGO:0061024 membrane organization TAS
 biological_processGO:0072583 clathrin-dependent endocytosis IEA
 biological_processGO:0072659 protein localization to plasma membrane ISS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0005905 clathrin-coated pit IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030136 clathrin-coated vesicle IDA
 cellular_componentGO:0098835 presynaptic endocytic zone membrane IEA
 molecular_functionGO:0001786 phosphatidylserine binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding ISS
 molecular_functionGO:0035091 phosphatidylinositol binding ISS
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000157107 FCHO2 / Q0JRZ9 / FCH domain only 2  / complex






 

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