ENSMUSG00000041685


Mus musculus

Features
Gene ID: ENSMUSG00000041685
  
Biological name :Fcho2
  
Synonyms : F-BAR domain only protein 2 / Fcho2 / Q3UQN2
  
Possible biological names infered from orthology : FCH domain only 2 / Q0JRZ9
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: D1
Gene start: 98723403
Gene end: 98815449
  
Corresponding Affymetrix probe sets: 10411464 (MoGene1.0st)   1437200_at (Mouse Genome 430 2.0 Array)   1442453_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000137422
Ensembl peptide - ENSMUSP00000153477
Ensembl peptide - ENSMUSP00000153040
Ensembl peptide - ENSMUSP00000042959
Ensembl peptide - ENSMUSP00000096883
Ensembl peptide - ENSMUSP00000105030
NCBI entrez gene - 218503     See in Manteia.
MGI - MGI:3505790
RefSeq - XM_011244652
RefSeq - NM_172591
RefSeq Peptide - NP_766179
swissprot - J3QPQ1
swissprot - A0A286YCL2
swissprot - A0A286YDL7
swissprot - Q3UQN2
swissprot - F6RG68
Ensembl - ENSMUSG00000041685
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000044064Gallus gallus
 ENSGALG00000015019Gallus gallus
 FCHO2ENSG00000157107Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fcho1 / Q8K285 / F-BAR domain only protein 1 / O14526* / FCH domain only 1*ENSMUSG0000007000040
Sgip1 / Q8VD37 / SH3-containing GRB2-like protein 3-interacting protein 1 / Q9BQI5* / SH3 domain GRB2 like endophilin interacting protein 1*ENSMUSG0000002852437


Protein motifs (from Interpro)
Interpro ID Name
 IPR001060  FCH domain
 IPR018808  Muniscin C-terminal
 IPR027267  AH/BAR domain superfamily
 IPR028565  Mu homology domain
 IPR030122  F-BAR domain only protein 2
 IPR031160  F-BAR domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0010324 membrane invagination IDA
 biological_processGO:0048268 clathrin coat assembly ISS
 biological_processGO:0048488 synaptic vesicle endocytosis IGI
 biological_processGO:0072583 clathrin-dependent endocytosis IEA
 biological_processGO:0072659 protein localization to plasma membrane IMP
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005905 clathrin-coated pit ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030136 clathrin-coated vesicle ISO
 cellular_componentGO:0098835 presynaptic endocytic zone membrane IEA
 molecular_functionGO:0001786 phosphatidylserine binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IDA
 molecular_functionGO:0035091 phosphatidylinositol binding IDA
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000041685 Fcho2 / Q3UQN2 / F-BAR domain only protein 2 / Q0JRZ9* / FCH domain only 2*  / complex






 

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