ENSMUSG00000070000


Mus musculus

Features
Gene ID: ENSMUSG00000070000
  
Biological name :Fcho1
  
Synonyms : F-BAR domain only protein 1 / Fcho1 / Q8K285
  
Possible biological names infered from orthology : FCH domain only 1 / O14526
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: B3.3
Gene start: 71708387
Gene end: 71725716
  
Corresponding Affymetrix probe sets: 10579609 (MoGene1.0st)   1428575_at (Mouse Genome 430 2.0 Array)   1436077_a_at (Mouse Genome 430 2.0 Array)   1436078_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000119273
Ensembl peptide - ENSMUSP00000117606
Ensembl peptide - ENSMUSP00000123554
Ensembl peptide - ENSMUSP00000123631
Ensembl peptide - ENSMUSP00000091151
Ensembl peptide - ENSMUSP00000116135
NCBI entrez gene - 74015     See in Manteia.
MGI - MGI:1921265
RefSeq - XM_011242331
RefSeq - NM_028715
RefSeq - XM_006509765
RefSeq - XM_006509766
RefSeq - XM_006509767
RefSeq - XM_006509770
RefSeq Peptide - NP_082991
swissprot - Q8K285
swissprot - D6RCG0
swissprot - F6VQ30
swissprot - D3Z6N2
swissprot - D3YYE9
Ensembl - ENSMUSG00000070000
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fcho1ENSDARG00000015356Danio rerio
 FCHO1ENSG00000130475Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fcho2 / Q3UQN2 / F-BAR domain only protein 2 / Q0JRZ9* / FCH domain only 2*ENSMUSG0000004168537
Sgip1 / Q8VD37 / SH3-containing GRB2-like protein 3-interacting protein 1 / Q9BQI5* / SH3 domain GRB2 like endophilin interacting protein 1*ENSMUSG0000002852423


Protein motifs (from Interpro)
Interpro ID Name
 IPR001060  FCH domain
 IPR018808  Muniscin C-terminal
 IPR027267  AH/BAR domain superfamily
 IPR028565  Mu homology domain
 IPR030121  F-BAR domain only protein 1
 IPR031160  F-BAR domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0048268 clathrin coat assembly ISS
 biological_processGO:0072583 clathrin-dependent endocytosis ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005905 clathrin-coated pit ISO
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0035612 AP-2 adaptor complex binding ISO


Pathways (from Reactome)
Pathway description
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000070000 Fcho1 / Q8K285 / F-BAR domain only protein 1 / O14526* / FCH domain only 1*  / complex






 

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contact: otassy@igbmc.fr