ENSG00000158486


Homo sapiens

Features
Gene ID: ENSG00000158486
  
Biological name :DNAH3
  
Synonyms : DNAH3 / dynein axonemal heavy chain 3 / Q8TD57
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p12.3
Gene start: 20933111
Gene end: 21159441
  
Corresponding Affymetrix probe sets: 1560803_at (Human Genome U133 Plus 2.0 Array)   1563290_at (Human Genome U133 Plus 2.0 Array)   215266_at (Human Genome U133 Plus 2.0 Array)   216415_at (Human Genome U133 Plus 2.0 Array)   220725_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000261383
NCBI entrez gene - 55567     See in Manteia.
OMIM - 603334
RefSeq - XM_017023432
RefSeq - NM_017539
RefSeq - XM_017023428
RefSeq - XM_017023429
RefSeq - XM_006721062
RefSeq - XM_011545882
RefSeq - XM_011545883
RefSeq - XM_011545885
RefSeq - XM_011545886
RefSeq - XM_011545888
RefSeq - XM_011545889
RefSeq - XM_017023426
RefSeq - XM_017023427
RefSeq Peptide - NP_060009
swissprot - Q8TD57
Ensembl - ENSG00000158486
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DNAH3ENSGALG00000002350Gallus gallus
 Dnah7bENSMUSG00000041144Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DNAH10 / Q8IVF4 / dynein axonemal heavy chain 10ENSG0000019765330
DNAH9 / Q9NYC9 / dynein axonemal heavy chain 9ENSG0000000717429
DNAH5 / Q8TE73 / dynein axonemal heavy chain 5ENSG0000003913928
Q8NCM8 / DYNC2H1 / dynein cytoplasmic 2 heavy chain 1ENSG0000018724022
DNHD1 / Q96M86 / dynein heavy chain domain 1ENSG0000017953217


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR004273  Dynein heavy chain domain
 IPR013602  Dynein heavy chain, domain-2
 IPR024317  Dynein heavy chain, AAA module D4
 IPR024743  Dynein heavy chain, coiled coil stalk
 IPR026983  Dynein heavy chain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR035699  Dynein heavy chain, hydrolytic ATP-binding dynein motor region D1
 IPR035706  Dynein heavy chain, ATP-binding dynein motor region D5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003341 cilium movement IBA
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0036159 inner dynein arm assembly IBA
 biological_processGO:0060285 cilium-dependent cell motility NAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005858 axonemal dynein complex NAS
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0030286 dynein complex IEA
 cellular_componentGO:0036156 inner dynein arm IBA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity NAS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008569 ATP-dependent microtubule motor activity, minus-end-directed IBA
 molecular_functionGO:0045503 dynein light chain binding IBA
 molecular_functionGO:0045505 dynein intermediate chain binding IBA
 molecular_functionGO:0051959 dynein light intermediate chain binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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