ENSG00000197653


Homo sapiens

Features
Gene ID: ENSG00000197653
  
Biological name :DNAH10
  
Synonyms : DNAH10 / dynein axonemal heavy chain 10 / Q8IVF4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q24.31
Gene start: 123762188
Gene end: 123936206
  
Corresponding Affymetrix probe sets: 1562462_at (Human Genome U133 Plus 2.0 Array)   1565339_at (Human Genome U133 Plus 2.0 Array)   229738_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000445308
Ensembl peptide - ENSP00000444761
Ensembl peptide - ENSP00000479072
Ensembl peptide - ENSP00000489675
Ensembl peptide - ENSP00000485079
Ensembl peptide - ENSP00000386770
NCBI entrez gene - 196385     See in Manteia.
OMIM - 605884
RefSeq - XM_017018962
RefSeq - XM_011538014
RefSeq - XM_011538015
RefSeq - XM_011538016
RefSeq - XM_011538017
RefSeq - XM_011538019
RefSeq - XM_017018960
RefSeq - XM_017018961
RefSeq - NM_207437
RefSeq - XM_005253555
RefSeq Peptide - NP_997320
swissprot - A0A096LNK1
swissprot - F5H515
swissprot - A0A1C7CYW8
swissprot - A0A087WV07
swissprot - Q8IVF4
swissprot - H0YGZ2
Ensembl - ENSG00000197653
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000043806Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DNAH5 / Q8TE73 / dynein axonemal heavy chain 5ENSG0000003913931
DNAH9 / Q9NYC9 / dynein axonemal heavy chain 9ENSG0000000717431
DNAH3 / Q8TD57 / dynein axonemal heavy chain 3ENSG0000015848628
Q8NCM8 / DYNC2H1 / dynein cytoplasmic 2 heavy chain 1ENSG0000018724022
DNHD1 / Q96M86 / dynein heavy chain domain 1ENSG0000017953216


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR004273  Dynein heavy chain domain
 IPR011704  ATPase, dynein-related, AAA domain
 IPR013594  Dynein heavy chain, domain-1
 IPR013602  Dynein heavy chain, domain-2
 IPR024317  Dynein heavy chain, AAA module D4
 IPR024743  Dynein heavy chain, coiled coil stalk
 IPR026983  Dynein heavy chain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR035699  Dynein heavy chain, hydrolytic ATP-binding dynein motor region D1
 IPR035706  Dynein heavy chain, ATP-binding dynein motor region D5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030286 dynein complex IBA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008569 ATP-dependent microtubule motor activity, minus-end-directed IBA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0045503 dynein light chain binding IBA
 molecular_functionGO:0045505 dynein intermediate chain binding IBA
 molecular_functionGO:0051959 dynein light intermediate chain binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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