ENSG00000158825


Homo sapiens

Features
Gene ID: ENSG00000158825
  
Biological name :CDA
  
Synonyms : CDA / cytidine deaminase / P32320
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.12
Gene start: 20588948
Gene end: 20618908
  
Corresponding Affymetrix probe sets: 205627_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000364212
NCBI entrez gene - 978     See in Manteia.
OMIM - 123920
RefSeq - NM_001785
RefSeq Peptide - NP_001776
swissprot - P32320
Ensembl - ENSG00000158825
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdaaENSDARG00000111188Danio rerio
 cdabENSDARG00000038199Danio rerio
 CDAENSGALG00000007382Gallus gallus
 CdaENSMUSG00000028755Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002125  Cytidine and deoxycytidylate deaminase domain
 IPR006262  Cytidine deaminase, homotetrameric
 IPR016192  APOBEC/CMP deaminase, zinc-binding
 IPR016193  Cytidine deaminase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007166 cell surface receptor signaling pathway NAS
 biological_processGO:0008655 pyrimidine-containing compound salvage NAS
 biological_processGO:0009972 cytidine deamination IDA
 biological_processGO:0019858 cytosine metabolic process TAS
 biological_processGO:0030308 negative regulation of cell growth IDA
 biological_processGO:0043097 pyrimidine nucleoside salvage TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045980 negative regulation of nucleotide metabolic process IDA
 biological_processGO:0051289 protein homotetramerization IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:1904724 tertiary granule lumen TAS
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0001882 nucleoside binding IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004126 cytidine deaminase activity EXP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Pyrimidine salvage


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000158825 CDA / P32320 / cytidine deaminase  / complex






 

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