ENSG00000158901


Homo sapiens

Features
Gene ID: ENSG00000158901
  
Biological name :WFDC8
  
Synonyms : Q8IUA0 / WAP four-disulfide core domain 8 / WFDC8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q13.12
Gene start: 45551153
Gene end: 45579326
  
Corresponding Affymetrix probe sets: 1554156_a_at (Human Genome U133 Plus 2.0 Array)   1554157_a_at (Human Genome U133 Plus 2.0 Array)   215276_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361735
Ensembl peptide - ENSP00000289953
NCBI entrez gene - 90199     See in Manteia.
RefSeq - XM_017028119
RefSeq - NM_130896
RefSeq - NM_181510
RefSeq Peptide - NP_570966
RefSeq Peptide - NP_852611
swissprot - Q8IUA0
swissprot - A0A140VK68
Ensembl - ENSG00000158901
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Wfdc8ENSMUSG00000070533Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O95925 / EPPIN-WFDC6 / EPPIN-WFDC6 readthroughENSG0000024913923
EPPIN / O95925 / epididymal peptidase inhibitorENSG0000010144818
WFDC6 / Q9BQY6 / WAP four-disulfide core domain 6ENSG0000024354310


Protein motifs (from Interpro)
Interpro ID Name
 IPR002223  Pancreatic trypsin inhibitor Kunitz domain
 IPR008197  WAP-type "four-disulfide core" domain
 IPR020901  Proteinase inhibitor I2, Kunitz, conserved site
 IPR036645  Elafin-like superfamily
 IPR036880  Pancreatic trypsin inhibitor Kunitz domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr