ENSG00000243543


Homo sapiens

Features
Gene ID: ENSG00000243543
  
Biological name :WFDC6
  
Synonyms : Q9BQY6 / WAP four-disulfide core domain 6 / WFDC6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q13.12
Gene start: 45534196
Gene end: 45539495
  
Corresponding Affymetrix probe sets: 1552396_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361755
Ensembl peptide - ENSP00000361750
NCBI entrez gene - 140870     See in Manteia.
RefSeq - NM_080827
RefSeq Peptide - NP_543017
swissprot - Q9BQY6
swissprot - A0A0K0K1K0
Ensembl - ENSG00000243543
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 F6ULY1ENSMUSG00000070531Mus musculus
 Q3UW55ENSMUSG00000074595Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O95925 / EPPIN-WFDC6 / EPPIN-WFDC6 readthroughENSG0000024913948
EPPIN / O95925 / epididymal peptidase inhibitorENSG0000010144848
WFDC8 / Q8IUA0 / WAP four-disulfide core domain 8ENSG0000015890127


Protein motifs (from Interpro)
Interpro ID Name
 IPR002223  Pancreatic trypsin inhibitor Kunitz domain
 IPR008197  WAP-type "four-disulfide core" domain
 IPR036645  Elafin-like superfamily
 IPR036880  Pancreatic trypsin inhibitor Kunitz domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr