ENSMUSG00000074595


Mus musculus

Features
Gene ID: ENSMUSG00000074595
  
Biological name :Wfdc6a
  
Synonyms : Q3UW55 / WAP four-disulfide core domain 6A / Wfdc6a
  
Possible biological names infered from orthology : Q9BQY6 / WAP four-disulfide core domain 6 / WFDC6
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H3
Gene start: 164579519
Gene end: 164585447
  
Corresponding Affymetrix probe sets: 10489503 (MoGene1.0st)   1457766_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000096694
Ensembl peptide - ENSMUSP00000104966
NCBI entrez gene - 209351     See in Manteia.
MGI - MGI:2684968
RefSeq - XM_011239408
RefSeq - NM_001033240
RefSeq - NM_001177848
RefSeq - XM_006499076
RefSeq Peptide - NP_001028412
RefSeq Peptide - NP_001171319
swissprot - Q3UW55
Ensembl - ENSMUSG00000074595
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 WFDC6ENSG00000243543Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Wfdc6b / F6ULY1 / WAP four-disulfide core domain 6B / WFDC6* / Q9BQY6* / WAP four-disulfide core domain 6*ENSMUSG0000007053176
Eppin / Q9DA01 / O95925* / EPPIN-WFDC6* / EPPIN-WFDC6 readthrough* / epididymal peptidase inhibitor*ENSMUSG0000001773353
Wfdc8 / Q4KUS1 / WAP four-disulfide core domain 8 / Q8IUA0*ENSMUSG0000007053331


Protein motifs (from Interpro)
Interpro ID Name
 IPR002223  Pancreatic trypsin inhibitor Kunitz domain
 IPR008197  WAP-type "four-disulfide core" domain
 IPR020901  Proteinase inhibitor I2, Kunitz, conserved site
 IPR036645  Elafin-like superfamily
 IPR036880  Pancreatic trypsin inhibitor Kunitz domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010466 negative regulation of peptidase activity ISO
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0042742 defense response to bacterium ISO
 biological_processGO:0051259 protein complex oligomerization ISO
 biological_processGO:0090281 negative regulation of calcium ion import ISO
 biological_processGO:1901318 negative regulation of flagellated sperm motility ISO
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0009986 cell surface ISO
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr