ENSMUSG00000017733


Mus musculus

Features
Gene ID: ENSMUSG00000017733
  
Biological name :Eppin
  
Synonyms : Eppin / Q9DA01
  
Possible biological names infered from orthology : epididymal peptidase inhibitor / EPPIN-WFDC6 / EPPIN-WFDC6 readthrough / O95925
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H3
Gene start: 164588343
Gene end: 164593594
  
Corresponding Affymetrix probe sets: 10489506 (MoGene1.0st)   1420588_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000099389
NCBI entrez gene - 75526     See in Manteia.
MGI - MGI:1922776
RefSeq - NM_029325
RefSeq Peptide - NP_083601
swissprot - Q9DA01
Ensembl - ENSMUSG00000017733
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EPPINENSG00000101448Homo sapiens
 O95925ENSG00000249139Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Wfdc6a / Q3UW55 / WAP four-disulfide core domain 6A / WFDC6* / Q9BQY6* / WAP four-disulfide core domain 6*ENSMUSG0000007459554
Wfdc6b / F6ULY1 / WAP four-disulfide core domain 6B / WFDC6* / Q9BQY6* / WAP four-disulfide core domain 6*ENSMUSG0000007053149
Wfdc8 / Q4KUS1 / WAP four-disulfide core domain 8 / Q8IUA0*ENSMUSG0000007053333


Protein motifs (from Interpro)
Interpro ID Name
 IPR002223  Pancreatic trypsin inhibitor Kunitz domain
 IPR008197  WAP-type "four-disulfide core" domain
 IPR020901  Proteinase inhibitor I2, Kunitz, conserved site
 IPR036645  Elafin-like superfamily
 IPR036880  Pancreatic trypsin inhibitor Kunitz domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010466 negative regulation of peptidase activity ISS
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0042742 defense response to bacterium ISS
 cellular_componentGO:0001669 acrosomal vesicle IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0009986 cell surface IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Antimicrobial peptides


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000032496 Ltf / P08071 / Lactotransferrin / P02788*  / complex
 ENSMUSG00000022037 Clu / Q06890 / Clusterin Clusterin beta chain Clusterin alpha chain / P10909* / clusterin*  / complex






 

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