ENSG00000160469


Homo sapiens

Features
Gene ID: ENSG00000160469
  
Biological name :BRSK1
  
Synonyms : BR serine/threonine kinase 1 / BRSK1 / Q8TDC3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.42
Gene start: 55282072
Gene end: 55312533
  
Corresponding Affymetrix probe sets: 1552504_a_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468190
Ensembl peptide - ENSP00000466755
Ensembl peptide - ENSP00000467357
Ensembl peptide - ENSP00000310649
Ensembl peptide - ENSP00000320853
Ensembl peptide - ENSP00000466380
NCBI entrez gene - 84446     See in Manteia.
OMIM - 609235
RefSeq - XM_011527395
RefSeq - NM_032430
RefSeq - XM_005259327
RefSeq Peptide - NP_115806
swissprot - J3KNK0
swissprot - Q8TDC3
swissprot - K7EM68
swissprot - K7EN26
Ensembl - ENSG00000160469
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Brsk1ENSMUSG00000035390Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BRSK2 / Q8IWQ3 / BR serine/threonine kinase 2ENSG0000017467268


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR015940  Ubiquitin-associated domain
 IPR017348  Serine/threonine-protein kinase pim-1/2/3
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007095 mitotic G2 DNA damage checkpoint IDA
 biological_processGO:0007269 neurotransmitter secretion ISS
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007409 axonogenesis ISS
 biological_processGO:0009411 response to UV IDA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030010 establishment of cell polarity ISS
 biological_processGO:0030182 neuron differentiation ISS
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0048812 neuron projection morphogenesis IEA
 biological_processGO:0051298 centrosome duplication ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IBA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0008021 synaptic vesicle ISS
 cellular_componentGO:0030054 cell junction IDA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IDA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0005524 ATP binding IC
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0043015 gamma-tubulin binding ISS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050321 tau-protein kinase activity ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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