ENSG00000160991


Homo sapiens

Features
Gene ID: ENSG00000160991
  
Biological name :ORAI2
  
Synonyms : ORAI2 / ORAI calcium release-activated calcium modulator 2 / Q96SN7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q22.1
Gene start: 102433106
Gene end: 102456821
  
Corresponding Affymetrix probe sets: 1558426_x_at (Human Genome U133 Plus 2.0 Array)   217529_at (Human Genome U133 Plus 2.0 Array)   218811_at (Human Genome U133 Plus 2.0 Array)   218812_s_at (Human Genome U133 Plus 2.0 Array)   230347_at (Human Genome U133 Plus 2.0 Array)   231406_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417928
Ensembl peptide - ENSP00000418140
Ensembl peptide - ENSP00000478113
Ensembl peptide - ENSP00000420178
Ensembl peptide - ENSP00000419416
Ensembl peptide - ENSP00000418464
Ensembl peptide - ENSP00000348752
Ensembl peptide - ENSP00000385489
Ensembl peptide - ENSP00000417407
NCBI entrez gene - 80228     See in Manteia.
OMIM - 610929
RefSeq - NM_032831
RefSeq - NM_001126340
RefSeq - NM_001271818
RefSeq - NM_001271819
RefSeq Peptide - NP_001119812
RefSeq Peptide - NP_001258747
RefSeq Peptide - NP_001258748
RefSeq Peptide - NP_116220
swissprot - Q96SN7
swissprot - C9JQR7
swissprot - C9J5L2
swissprot - C9J2H9
swissprot - C9JUY6
Ensembl - ENSG00000160991
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 orai2ENSDARG00000035148Danio rerio
 ORAI2ENSGALG00000001837Gallus gallus
 Orai2ENSMUSG00000039747Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ORAI1 / Q96D31 / ORAI calcium release-activated calcium modulator 1ENSG0000027604563
ORAI3 / Q9BRQ5 / ORAI calcium release-activated calcium modulator 3ENSG0000017593859


Protein motifs (from Interpro)
Interpro ID Name
 IPR012446  Calcium release-activated calcium channel protein
 IPR030034  Protein Orai-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002115 store-operated calcium entry IBA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0016020 membrane IBA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030426 growth cone IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015279 store-operated calcium channel activity IBA


Pathways (from Reactome)
Pathway description
Elevation of cytosolic Ca2+ levels
Ion homeostasis
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000160991 ORAI2 / Q96SN7 / ORAI calcium release-activated calcium modulator 2  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr