ENSG00000161544


Homo sapiens

Features
Gene ID: ENSG00000161544
  
Biological name :CYGB
  
Synonyms : CYGB / cytoglobin / Q8WWM9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q25.1
Gene start: 76527356
Gene end: 76551175
  
Corresponding Affymetrix probe sets: 1553572_a_at (Human Genome U133 Plus 2.0 Array)   1570410_at (Human Genome U133 Plus 2.0 Array)   226632_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464817
Ensembl peptide - ENSP00000468559
Ensembl peptide - ENSP00000466448
Ensembl peptide - ENSP00000293230
NCBI entrez gene - 114757     See in Manteia.
OMIM - 608759
RefSeq - NM_134268
RefSeq Peptide - NP_599030
swissprot - Q8WWM9
swissprot - K7EMC7
swissprot - K7EIM9
swissprot - A0A1K0FUB6
Ensembl - ENSG00000161544
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cygb1ENSDARG00000099371Danio rerio
 cygb2ENSDARG00000070148Danio rerio
 CYGBENSGALG00000001892Gallus gallus
 CygbENSMUSG00000020810Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MB / P02144 / myoglobinENSG0000019812522


Protein motifs (from Interpro)
Interpro ID Name
 IPR000971  Globin
 IPR009050  Globin-like superfamily
 IPR013314  Globin, lamprey/hagfish type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0006979 response to oxidative stress ISS
 biological_processGO:0010764 negative regulation of fibroblast migration IEA
 biological_processGO:0015671 oxygen transport IEA
 biological_processGO:0019395 fatty acid oxidation IEA
 biological_processGO:0032966 negative regulation of collagen biosynthetic process IEA
 biological_processGO:0050999 regulation of nitric-oxide synthase activity TAS
 biological_processGO:0098869 cellular oxidant detoxification IEA
 biological_processGO:2000490 negative regulation of hepatic stellate cell activation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0004096 catalase activity IEA
 molecular_functionGO:0004601 peroxidase activity IEA
 molecular_functionGO:0005344 oxygen carrier activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008941 nitric oxide dioxygenase activity TAS
 molecular_functionGO:0019825 oxygen binding IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047888 fatty acid peroxidase activity IEA


Pathways (from Reactome)
Pathway description
eNOS activation
Intracellular oxygen transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000161544 CYGB / Q8WWM9 / cytoglobin  / complex






 

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