ENSG00000163563


Homo sapiens

Features
Gene ID: ENSG00000163563
  
Biological name :MNDA
  
Synonyms : MNDA / myeloid cell nuclear differentiation antigen / P41218
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q23.1
Gene start: 158831317
Gene end: 158849506
  
Corresponding Affymetrix probe sets: 204959_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357123
Ensembl peptide - ENSP00000406800
NCBI entrez gene - 4332     See in Manteia.
OMIM - 159553
RefSeq - NM_002432
RefSeq Peptide - NP_002423
swissprot - Q5VUU6
swissprot - H0Y6P3
swissprot - P41218
Ensembl - ENSG00000163563
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PYHIN1 / Q6K0P9 / pyrin and HIN domain family member 1ENSG0000016356452
IFI16 / Q16666 / interferon gamma inducible protein 16ENSG0000016356550
AIM2 / O14862 / absent in melanoma 2ENSG0000016356830


Protein motifs (from Interpro)
Interpro ID Name
 IPR004020  DAPIN domain
 IPR004021  HIN-200/IF120x


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006968 cellular defense response TAS
 biological_processGO:0006974 cellular response to DNA damage stimulus IMP
 biological_processGO:0030889 negative regulation of B cell proliferation IMP
 biological_processGO:0043065 positive regulation of apoptotic process IMP
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0050853 B cell receptor signaling pathway IMP
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0035578 azurophil granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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