ENSG00000163697


Homo sapiens

Features
Gene ID: ENSG00000163697
  
Biological name :APBB2
  
Synonyms : amyloid beta precursor protein binding family B member 2 / APBB2 / Q92870
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: p13
Gene start: 40810027
Gene end: 41216714
  
Corresponding Affymetrix probe sets: 212970_at (Human Genome U133 Plus 2.0 Array)   212972_x_at (Human Genome U133 Plus 2.0 Array)   212985_at (Human Genome U133 Plus 2.0 Array)   213419_at (Human Genome U133 Plus 2.0 Array)   216747_at (Human Genome U133 Plus 2.0 Array)   216750_at (Human Genome U133 Plus 2.0 Array)   40148_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000425121
Ensembl peptide - ENSP00000424579
Ensembl peptide - ENSP00000425202
Ensembl peptide - ENSP00000439357
Ensembl peptide - ENSP00000427307
Ensembl peptide - ENSP00000427211
Ensembl peptide - ENSP00000427107
Ensembl peptide - ENSP00000426429
Ensembl peptide - ENSP00000426018
Ensembl peptide - ENSP00000425802
Ensembl peptide - ENSP00000295974
Ensembl peptide - ENSP00000421205
Ensembl peptide - ENSP00000421301
Ensembl peptide - ENSP00000421539
Ensembl peptide - ENSP00000421751
Ensembl peptide - ENSP00000422723
Ensembl peptide - ENSP00000422948
Ensembl peptide - ENSP00000423765
Ensembl peptide - ENSP00000424414
NCBI entrez gene - 323     See in Manteia.
OMIM - 602710
RefSeq - XM_017008159
RefSeq - XM_006714010
RefSeq - XM_006714011
RefSeq - XM_006714012
RefSeq - XM_011513686
RefSeq - XM_011513687
RefSeq - XM_011513688
RefSeq - XM_017008142
RefSeq - XM_017008143
RefSeq - XM_017008144
RefSeq - XM_017008145
RefSeq - XM_017008146
RefSeq - XM_017008147
RefSeq - XM_017008148
RefSeq - XM_017008149
RefSeq - XM_017008150
RefSeq - XM_017008151
RefSeq - XM_017008152
RefSeq - XM_017008153
RefSeq - XM_017008154
RefSeq - XM_017008155
RefSeq - XM_017008156
RefSeq - XM_017008157
RefSeq - XM_017008158
RefSeq - NM_001166050
RefSeq - NM_001166051
RefSeq - NM_001166052
RefSeq - NM_001166053
RefSeq - NM_001166054
RefSeq - NM_004307
RefSeq - NM_173075
RefSeq - XM_005248101
RefSeq - XM_006714005
RefSeq - XM_006714007
RefSeq - XM_006714008
RefSeq - XM_006714009
RefSeq Peptide - NP_001317587
RefSeq Peptide - NP_004298
RefSeq Peptide - NP_775098
RefSeq Peptide - NP_001159526
RefSeq Peptide - NP_001317585
RefSeq Peptide - NP_001159522
RefSeq Peptide - NP_001159523
RefSeq Peptide - NP_001159524
RefSeq Peptide - NP_001159525
swissprot - H0Y9U9
swissprot - H0YA92
swissprot - D6RGD4
swissprot - Q92870
swissprot - A0A1D5RMR3
swissprot - H0YAJ5
swissprot - D6RDY3
swissprot - D6RD19
swissprot - D6RB55
swissprot - D6RB00
swissprot - D6RAJ4
swissprot - D6RAE0
swissprot - G5E9Y1
swissprot - H0Y943
Ensembl - ENSG00000163697
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 apbb2bENSDARG00000099995Danio rerio
 APBB2ENSGALG00000014262Gallus gallus
 Apbb2ENSMUSG00000029207Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
APBB1 / O00213 / amyloid beta precursor protein binding family B member 1ENSG0000016631339
APBB3 / O95704 / amyloid beta precursor protein binding family B member 3ENSG0000011310822


Protein motifs (from Interpro)
Interpro ID Name
 IPR001202  WW domain
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR036020  WW domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0007050 cell cycle arrest ISS
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0030198 extracellular matrix organization IEA
 biological_processGO:0030308 negative regulation of cell growth ISS
 biological_processGO:0035556 intracellular signal transduction NAS
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016020 membrane NAS
 cellular_componentGO:0030027 lamellipodium ISS
 cellular_componentGO:0030426 growth cone ISS
 cellular_componentGO:0045202 synapse ISS
 molecular_functionGO:0001540 amyloid-beta binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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