ENSG00000164300


Homo sapiens

Features
Gene ID: ENSG00000164300
  
Biological name :SERINC5
  
Synonyms : Q86VE9 / SERINC5 / serine incorporator 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q14.1
Gene start: 80111651
Gene end: 80256079
  
Corresponding Affymetrix probe sets: 212812_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000488864
Ensembl peptide - ENSP00000421665
Ensembl peptide - ENSP00000426134
Ensembl peptide - ENSP00000426237
NCBI entrez gene - 256987     See in Manteia.
OMIM - 614551
RefSeq - XM_017009326
RefSeq - NM_001174071
RefSeq - NM_001174072
RefSeq - NM_178276
RefSeq - XM_011543304
RefSeq - XM_017009323
RefSeq - XM_017009324
RefSeq - XM_017009325
RefSeq Peptide - NP_001167542
RefSeq Peptide - NP_001167543
RefSeq Peptide - NP_840060
swissprot - A0A0J9YYI4
swissprot - Q86VE9
Ensembl - ENSG00000164300
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q803X0ENSDARG00000008153Danio rerio
 SERINC5ENSGALG00000014798Gallus gallus
 Q8BHJ6ENSMUSG00000021703Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A6NH21 / SERINC4 / serine incorporator 4ENSG0000018471641
Q9NRX5 / SERINC1 / serine incorporator 1ENSG0000011189738
Q13530 / SERINC3 / serine incorporator 3ENSG0000013282438
Q96SA4 / SERINC2 / serine incorporator 2ENSG0000016852837


Protein motifs (from Interpro)
Interpro ID Name
 IPR005016  Serine incorporator/TMS membrane protein
 IPR029555  Serine incorporator 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006564 L-serine biosynthetic process TAS
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006658 phosphatidylserine metabolic process ISS
 biological_processGO:0006665 sphingolipid metabolic process IEA
 biological_processGO:0008654 phospholipid biosynthetic process IEA
 biological_processGO:0009597 detection of virus IDA
 biological_processGO:0015825 L-serine transport IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0042552 myelination IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:1904219 positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity ISS
 biological_processGO:1904222 positive regulation of serine C-palmitoyltransferase activity ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0015194 L-serine transmembrane transporter activity TAS


Pathways (from Reactome)
Pathway description
Serine biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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