ENSG00000132824


Homo sapiens

Features
Gene ID: ENSG00000132824
  
Biological name :SERINC3
  
Synonyms : Q13530 / SERINC3 / serine incorporator 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q13.12
Gene start: 44496221
Gene end: 44522109
  
Corresponding Affymetrix probe sets: 211769_x_at (Human Genome U133 Plus 2.0 Array)   221471_at (Human Genome U133 Plus 2.0 Array)   221472_at (Human Genome U133 Plus 2.0 Array)   221473_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000255175
Ensembl peptide - ENSP00000340243
Ensembl peptide - ENSP00000414197
NCBI entrez gene - 10955     See in Manteia.
OMIM - 607165
RefSeq - XM_017027601
RefSeq - NM_006811
RefSeq - NM_198941
RefSeq Peptide - NP_945179
RefSeq Peptide - NP_006802
swissprot - Q13530
swissprot - Q5H936
Ensembl - ENSG00000132824
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch73-267c23.10ENSDARG00000111669Danio rerio
 si:ch73-267c23.10ENSDARG00000086133Danio rerio
 SERINC3ENSGALG00000004220Gallus gallus
 Q9QZI9ENSMUSG00000017707Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NRX5 / SERINC1 / serine incorporator 1ENSG0000011189759
Q96SA4 / SERINC2 / serine incorporator 2ENSG0000016852849
Q86VE9 / SERINC5 / serine incorporator 5ENSG0000016430037
A6NH21 / SERINC4 / serine incorporator 4ENSG0000018471630


Protein motifs (from Interpro)
Interpro ID Name
 IPR005016  Serine incorporator/TMS membrane protein
 IPR029557  Serine incorporator 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006564 L-serine biosynthetic process TAS
 biological_processGO:0006658 phosphatidylserine metabolic process IEA
 biological_processGO:0006665 sphingolipid metabolic process IEA
 biological_processGO:0009597 detection of virus IDA
 biological_processGO:0015825 L-serine transport IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0015194 L-serine transmembrane transporter activity TAS


Pathways (from Reactome)
Pathway description
Serine biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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