ENSMUSG00000017707


Mus musculus

Features
Gene ID: ENSMUSG00000017707
  
Biological name :Serinc3
  
Synonyms : Q9QZI9 / Serinc3 / Serine incorporator 3
  
Possible biological names infered from orthology : Q13530
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H3
Gene start: 163623272
Gene end: 163645131
  
Corresponding Affymetrix probe sets: 10489377 (MoGene1.0st)   1417815_a_at (Mouse Genome 430 2.0 Array)   1417816_s_at (Mouse Genome 430 2.0 Array)   1434548_at (Mouse Genome 430 2.0 Array)   1448847_at (Mouse Genome 430 2.0 Array)   1455550_x_at (Mouse Genome 430 2.0 Array)   1456080_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000017851
NCBI entrez gene - 26943     See in Manteia.
MGI - MGI:1349457
RefSeq - NM_012032
RefSeq - XM_006499616
RefSeq Peptide - NP_036162
swissprot - Q9QZI9
Ensembl - ENSMUSG00000017707
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch73-267c23.10ENSDARG00000111669Danio rerio
 si:ch73-267c23.10ENSDARG00000086133Danio rerio
 SERINC3ENSGALG00000004220Gallus gallus
 Q13530ENSG00000132824Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9QZI8 / Serinc1 / Serine incorporator 1 / Q9NRX5*ENSMUSG0000001987757
Q8K0E7 / Serinc2 / Serine incorporator 2 / Q96SA4*ENSMUSG0000002323249
Q8BHJ6 / Serinc5 / Serine incorporator 5 / Q86VE9*ENSMUSG0000002170337
Q5XK03 / Serinc4 / Serine incorporator 4 / A6NH21*ENSMUSG0000004611028


Protein motifs (from Interpro)
Interpro ID Name
 IPR005016  Serine incorporator/TMS membrane protein
 IPR029557  Serine incorporator 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006658 phosphatidylserine metabolic process IEA
 biological_processGO:0006665 sphingolipid metabolic process IEA
 biological_processGO:0009597 detection of virus IEA
 biological_processGO:0015825 L-serine transport IEA
 biological_processGO:0045087 innate immune response ISO
 biological_processGO:0051607 defense response to virus ISO
 biological_processGO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IDA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0015194 L-serine transmembrane transporter activity IBA


Pathways (from Reactome)
Pathway description
Serine biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1ltm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0003345 decreased number of ribs "fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1ltm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0010093 decreased circulating magnesium level "a reduction in the blood concentration of magnesium" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1ltm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1ltm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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