ENSMUSG00000019877


Mus musculus

Features
Gene ID: ENSMUSG00000019877
  
Biological name :Serinc1
  
Synonyms : Q9QZI8 / Serinc1 / Serine incorporator 1
  
Possible biological names infered from orthology : Q9NRX5
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: B4
Gene start: 57515774
Gene end: 57532530
  
Corresponding Affymetrix probe sets: 10369210 (MoGene1.0st)   1415838_at (Mouse Genome 430 2.0 Array)   1437513_a_at (Mouse Genome 430 2.0 Array)   1448108_at (Mouse Genome 430 2.0 Array)   1454811_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020027
Ensembl peptide - ENSMUSP00000127041
Ensembl peptide - ENSMUSP00000126561
NCBI entrez gene - 56442     See in Manteia.
MGI - MGI:1926228
RefSeq - NM_019760
RefSeq Peptide - NP_062734
swissprot - E9PY81
swissprot - A9CLV6
swissprot - E9Q553
swissprot - Q9QZI8
Ensembl - ENSMUSG00000019877
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 serinc1ENSDARG00000009106Danio rerio
 SERINC1ENSGALG00000014868Gallus gallus
 Q9NRX5ENSG00000111897Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9QZI9 / Serinc3 / Serine incorporator 3 / Q13530*ENSMUSG0000001770759
Q8K0E7 / Serinc2 / Serine incorporator 2 / Q96SA4*ENSMUSG0000002323253
Q8BHJ6 / Serinc5 / Serine incorporator 5 / Q86VE9*ENSMUSG0000002170339
Q5XK03 / Serinc4 / Serine incorporator 4 / A6NH21*ENSMUSG0000004611033


Protein motifs (from Interpro)
Interpro ID Name
 IPR005016  Serine incorporator/TMS membrane protein
 IPR029552  Serine incorporator 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006658 phosphatidylserine metabolic process IEA
 biological_processGO:0006665 sphingolipid metabolic process IEA
 biological_processGO:0008654 phospholipid biosynthetic process IEA
 biological_processGO:0015825 L-serine transport IEA
 biological_processGO:0044091 membrane biogenesis ISS
 biological_processGO:1904219 positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity ISS
 biological_processGO:1904222 positive regulation of serine C-palmitoyltransferase activity ISS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0015194 L-serine transmembrane transporter activity IBA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0030674 protein binding, bridging ISS


Pathways (from Reactome)
Pathway description
Serine biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cdkn2atm2.1Brn/Cdkn2atm2.1Brn,Hdac2tm1.2Rdp/Hdac2tm1.2Rdp
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Cdkn2atm2.1Brn/Cdkn2atm2.1Brn,Hdac2tm1.2Rdp/Hdac2tm1.2Rdp
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Cdkn2atm2.1Brn/Cdkn2atm2.1Brn,Hdac2tm1.2Rdp/Hdac2tm1.2Rdp
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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