ENSG00000111897


Homo sapiens

Features
Gene ID: ENSG00000111897
  
Biological name :SERINC1
  
Synonyms : Q9NRX5 / SERINC1 / serine incorporator 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q22.31
Gene start: 122443354
Gene end: 122471822
  
Corresponding Affymetrix probe sets: 208671_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000342962
NCBI entrez gene - 57515     See in Manteia.
OMIM - 614548
RefSeq - NM_020755
RefSeq Peptide - NP_065806
swissprot - Q9NRX5
Ensembl - ENSG00000111897
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 serinc1ENSDARG00000009106Danio rerio
 SERINC1ENSGALG00000014868Gallus gallus
 Q9QZI8ENSMUSG00000019877Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q13530 / SERINC3 / serine incorporator 3ENSG0000013282461
Q96SA4 / SERINC2 / serine incorporator 2ENSG0000016852853
Q86VE9 / SERINC5 / serine incorporator 5ENSG0000016430039
A6NH21 / SERINC4 / serine incorporator 4ENSG0000018471635


Protein motifs (from Interpro)
Interpro ID Name
 IPR005016  Serine incorporator/TMS membrane protein
 IPR029552  Serine incorporator 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006658 phosphatidylserine metabolic process ISS
 biological_processGO:0006665 sphingolipid metabolic process ISS
 biological_processGO:0008654 phospholipid biosynthetic process IEA
 biological_processGO:0015825 L-serine transport IEA
 biological_processGO:0044091 membrane biogenesis IEA
 biological_processGO:1904219 positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity IEA
 biological_processGO:1904222 positive regulation of serine C-palmitoyltransferase activity IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane ISS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015194 L-serine transmembrane transporter activity IBA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0030674 protein binding, bridging IEA


Pathways (from Reactome)
Pathway description
Serine biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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