ENSG00000164303


Homo sapiens

Features
Gene ID: ENSG00000164303
  
Biological name :ENPP6
  
Synonyms : ectonucleotide pyrophosphatase/phosphodiesterase 6 / ENPP6 / Q6UWR7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q35.1
Gene start: 184088706
Gene end: 184221230
  
Corresponding Affymetrix probe sets: 229916_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000296741
Ensembl peptide - ENSP00000423497
NCBI entrez gene - 133121     See in Manteia.
OMIM - 616983
RefSeq - NM_153343
RefSeq Peptide - NP_699174
swissprot - D6R9P1
swissprot - Q6UWR7
Ensembl - ENSG00000164303
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 enpp6ENSDARG00000040469Danio rerio
 ENPP6ENSGALG00000010645Gallus gallus
 Enpp6ENSMUSG00000038173Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENPP5 / Q9UJA9 / ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)ENSG0000011279633
ENPP4 / Q9Y6X5 / ectonucleotide pyrophosphatase/phosphodiesterase 4ENSG0000000156131
ENPP1 / P22413 / ectonucleotide pyrophosphatase/phosphodiesterase 1ENSG0000019759430
ENPP7 / Q6UWV6 / ectonucleotide pyrophosphatase/phosphodiesterase 7ENSG0000018215630
ENPP3 / O14638 / ectonucleotide pyrophosphatase/phosphodiesterase 3ENSG0000015426928
ENPP2 / Q13822 / ectonucleotide pyrophosphatase/phosphodiesterase 2ENSG0000013696024


Protein motifs (from Interpro)
Interpro ID Name
 IPR002591  Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase
 IPR017849  Alkaline phosphatase-like, alpha/beta/alpha
 IPR017850  Alkaline-phosphatase-like, core domain superfamily
 IPR029889  Ectonucleotide pyrophosphatase/phosphodiesterase family member 6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0019695 choline metabolic process IDA
 biological_processGO:0046475 glycerophospholipid catabolic process TAS
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IDA
 molecular_functionGO:0008889 glycerophosphodiester phosphodiesterase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0047390 glycerophosphocholine cholinephosphodiesterase activity IEA


Pathways (from Reactome)
Pathway description
Glycerophospholipid catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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