ENSG00000182156


Homo sapiens

Features
Gene ID: ENSG00000182156
  
Biological name :ENPP7
  
Synonyms : ectonucleotide pyrophosphatase/phosphodiesterase 7 / ENPP7 / Q6UWV6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q25.3
Gene start: 79730919
Gene end: 79742222
  
Corresponding Affymetrix probe sets: 238245_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000332656
Ensembl peptide - ENSP00000460429
NCBI entrez gene - 339221     See in Manteia.
OMIM - 616997
RefSeq - XM_011524737
RefSeq - NM_178543
RefSeq Peptide - NP_848638
swissprot - Q6UWV6
swissprot - I3L3G5
Ensembl - ENSG00000182156
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 enpp7.1ENSDARG00000053526Danio rerio
 enpp7.2ENSDARG00000053525Danio rerio
 ENPP7ENSGALG00000013743Gallus gallus
 Enpp7ENSMUSG00000046697Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENPP5 / Q9UJA9 / ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)ENSG0000011279633
ENPP1 / P22413 / ectonucleotide pyrophosphatase/phosphodiesterase 1ENSG0000019759430
ENPP3 / O14638 / ectonucleotide pyrophosphatase/phosphodiesterase 3ENSG0000015426929
ENPP4 / Q9Y6X5 / ectonucleotide pyrophosphatase/phosphodiesterase 4ENSG0000000156128
ENPP6 / Q6UWR7 / ectonucleotide pyrophosphatase/phosphodiesterase 6ENSG0000016430328
ENPP2 / Q13822 / ectonucleotide pyrophosphatase/phosphodiesterase 2ENSG0000013696026


Protein motifs (from Interpro)
Interpro ID Name
 IPR002591  Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase
 IPR017849  Alkaline phosphatase-like, alpha/beta/alpha
 IPR017850  Alkaline-phosphatase-like, core domain superfamily
 IPR029895  Ectonucleotide pyrophosphatase/phosphodiesterase family member 7


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006684 sphingomyelin metabolic process IDA
 biological_processGO:0006685 sphingomyelin catabolic process IEA
 biological_processGO:0006687 glycosphingolipid metabolic process TAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0008156 negative regulation of DNA replication IDA
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005902 microvillus IDA
 cellular_componentGO:0016020 membrane NAS
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004767 sphingomyelin phosphodiesterase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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