ENSG00000164347


Homo sapiens

Features
Gene ID: ENSG00000164347
  
Biological name :GFM2
  
Synonyms : G elongation factor mitochondrial 2 / GFM2 / Q969S9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q13.3
Gene start: 74721204
Gene end: 74767371
  
Corresponding Affymetrix probe sets: 225392_at (Human Genome U133 Plus 2.0 Array)   231917_at (Human Genome U133 Plus 2.0 Array)   231918_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000424877
Ensembl peptide - ENSP00000296804
Ensembl peptide - ENSP00000427004
Ensembl peptide - ENSP00000296805
Ensembl peptide - ENSP00000421717
Ensembl peptide - ENSP00000405808
NCBI entrez gene - 84340     See in Manteia.
OMIM - 606544
RefSeq - XM_017009986
RefSeq - NM_001281302
RefSeq - NM_032380
RefSeq - NM_170681
RefSeq - NM_170691
RefSeq - XM_011543691
RefSeq Peptide - NP_115756
RefSeq Peptide - NP_001268231
RefSeq Peptide - NP_733781
RefSeq Peptide - NP_733792
swissprot - A0A024RAJ7
swissprot - D6RAL1
swissprot - D6RF75
swissprot - Q969S9
swissprot - A0A024RAK1
Ensembl - ENSG00000164347
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gfm2ENSDARG00000005561Danio rerio
 GFM2ENSGALG00000014939Gallus gallus
 Gfm2ENSMUSG00000021666Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000640  Elongation factor EFG, domain V-like
 IPR000795  Transcription factor, GTP-binding domain
 IPR004161  Translation elongation factor EFTu-like, domain 2
 IPR005225  Small GTP-binding protein domain
 IPR005517  Translation elongation factor EFG/EF2, domain IV
 IPR009000  Translation protein, beta-barrel domain superfamily
 IPR009022  Elongation factor G, domain III
 IPR014721  Ribosomal protein S5 domain 2-type fold, subgroup
 IPR020568  Ribosomal protein S5 domain 2-type fold
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030851  Ribosome-releasing factor 2, mitochondrial
 IPR031157  Tr-type G domain, conserved site
 IPR035647  EF-G domain III/V-like
 IPR035649  EFG, domain V


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006414 translational elongation IEA
 biological_processGO:0032543 mitochondrial translation IDA
 biological_processGO:0032790 ribosome disassembly IDA
 biological_processGO:0070126 mitochondrial translational termination TAS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003746 translation elongation factor activity IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Mitochondrial translation termination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000148187 MRRF / Q96E11 / mitochondrial ribosome recycling factor  / reaction / complex






 

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