ENSG00000164363


Homo sapiens

Features
Gene ID: ENSG00000164363
  
Biological name :SLC6A18
  
Synonyms : Q96N87 / SLC6A18 / solute carrier family 6 member 18
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: p15.33
Gene start: 1225355
Gene end: 1246189
  
Corresponding Affymetrix probe sets: 238215_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000323549
NCBI entrez gene - 348932     See in Manteia.
OMIM - 610300
RefSeq - NM_182632
RefSeq Peptide - NP_872438
swissprot - Q96N87
Ensembl - ENSG00000164363
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc6a18ENSDARG00000068387Danio rerio
 SLC6A18ENSGALG00000013180Gallus gallus
 O88576ENSMUSG00000021612Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q695T7 / SLC6A19 / solute carrier family 6 member 19ENSG0000017435851
Q9NP91 / SLC6A20 / solute carrier family 6 member 20ENSG0000016381745
Q9H2J7 / SLC6A15 / solute carrier family 6 member 15ENSG0000007204140
Q9H1V8 / SLC6A17 / solute carrier family 6 member 17ENSG0000019710639
Q9GZN6 / SLC6A16 / solute carrier family 6 member 16ENSG0000006312729


Protein motifs (from Interpro)
Interpro ID Name
 IPR000175  Sodium:neurotransmitter symporter
 IPR002438  Sodium:neurotransmitter symporter, orphan
 IPR037272  Sodium:neurotransmitter symporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003333 amino acid transmembrane transport IEA
 biological_processGO:0006836 neurotransmitter transport IEA
 biological_processGO:0006865 amino acid transport TAS
 biological_processGO:0015804 neutral amino acid transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031526 brush border membrane IEA
 molecular_functionGO:0005215 transporter activity IBA
 molecular_functionGO:0005328 neurotransmitter:sodium symporter activity IEA
 molecular_functionGO:0015171 amino acid transmembrane transporter activity TAS
 molecular_functionGO:0015175 neutral amino acid transmembrane transporter activity IEA
 molecular_functionGO:0015293 symporter activity IEA


Pathways (from Reactome)
Pathway description
Amino acid transport across the plasma membrane
Na+/Cl- dependent neurotransmitter transporters
Defective SLC6A18 may confer susceptibility to iminoglycinuria and/or hyperglycinuria
Defective SLC6A18 may confer susceptibility to iminoglycinuria and/or hyperglycinuria


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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