ENSG00000165030


Homo sapiens

Features
Gene ID: ENSG00000165030
  
Biological name :NFIL3
  
Synonyms : NFIL3 / nuclear factor, interleukin 3 regulated / Q16649
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q22.31
Gene start: 91409045
Gene end: 91423862
  
Corresponding Affymetrix probe sets: 203574_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000297689
NCBI entrez gene - 4783     See in Manteia.
OMIM - 605327
RefSeq - NM_005384
RefSeq - XM_017014744
RefSeq - NM_001289999
RefSeq - NM_001290000
RefSeq - XM_017014743
RefSeq Peptide - NP_001276929
RefSeq Peptide - NP_005375
RefSeq Peptide - NP_001276928
swissprot - Q16649
swissprot - A0A024R241
Ensembl - ENSG00000165030
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nfil3ENSDARG00000042977Danio rerio
 NFIL3ENSGALG00000015209Gallus gallus
 Nfil3ENSMUSG00000056749Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004827  Basic-leucine zipper domain
 IPR010533  Vertebrate interleukin-3 regulated transcription factor
 IPR016743  Nuclear factor interleukin-3-regulated protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006955 immune response TAS
 biological_processGO:0007623 circadian rhythm IBA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0071353 cellular response to interleukin-4 IEA
 cellular_componentGO:0005634 nucleus TAS
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0003714 transcription corepressor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Circadian Clock


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000123095 Q9C0J9 / BHLHE41 / basic helix-loop-helix family member e41  / complex






 

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