ENSG00000165475


Homo sapiens

Features
Gene ID: ENSG00000165475
  
Biological name :CRYL1
  
Synonyms : CRYL1 / crystallin lambda 1 / Q9Y2S2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q12.11
Gene start: 20403666
Gene end: 20525873
  
Corresponding Affymetrix probe sets: 220753_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000494794
Ensembl peptide - ENSP00000496154
Ensembl peptide - ENSP00000495342
Ensembl peptide - ENSP00000495054
Ensembl peptide - ENSP00000298248
Ensembl peptide - ENSP00000372262
Ensembl peptide - ENSP00000479908
Ensembl peptide - ENSP00000493784
Ensembl peptide - ENSP00000493818
Ensembl peptide - ENSP00000494114
NCBI entrez gene - 51084     See in Manteia.
OMIM - 609877
RefSeq - NM_015974
RefSeq - XM_005266415
RefSeq - XM_005266416
RefSeq - XM_017020624
RefSeq Peptide - NP_057058
swissprot - Q9Y2S2
swissprot - A0A024RDM2
swissprot - A0A087WW38
swissprot - V9HWG2
Ensembl - ENSG00000165475
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cryl1ENSDARG00000003675Danio rerio
 CRYL1ENSGALG00000017135Gallus gallus
 Cryl1ENSMUSG00000021947Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006108  3-hydroxyacyl-CoA dehydrogenase, C-terminal
 IPR006176  3-hydroxyacyl-CoA dehydrogenase, NAD binding
 IPR006180  3-hydroxyacyl-CoA dehydrogenase, conserved site
 IPR008927  6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
 IPR013328  6-phosphogluconate dehydrogenase, domain 2
 IPR022694  3-hydroxyacyl-CoA dehydrogenase
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0019640 glucuronate catabolic process to xylulose 5-phosphate TAS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003857 3-hydroxyacyl-CoA dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0050104 L-gulonate 3-dehydrogenase activity EXP
 molecular_functionGO:0070403 NAD+ binding IEA


Pathways (from Reactome)
Pathway description
Formation of xylulose-5-phosphate


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000165475 CRYL1 / Q9Y2S2 / crystallin lambda 1  / complex






 

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