ENSG00000165637


Homo sapiens

Features
Gene ID: ENSG00000165637
  
Biological name :VDAC2
  
Synonyms : P45880 / VDAC2 / voltage dependent anion channel 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q22.2
Gene start: 75210154
Gene end: 75231448
  
Corresponding Affymetrix probe sets: 211662_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361686
Ensembl peptide - ENSP00000361635
Ensembl peptide - ENSP00000389551
Ensembl peptide - ENSP00000443092
Ensembl peptide - ENSP00000401492
Ensembl peptide - ENSP00000298468
Ensembl peptide - ENSP00000344876
NCBI entrez gene - 7417     See in Manteia.
OMIM - 193245
RefSeq - NM_001324087
RefSeq - NM_001184783
RefSeq - NM_001184823
RefSeq - NM_001324088
RefSeq - NM_001324089
RefSeq - NM_001324090
RefSeq - NM_003375
RefSeq Peptide - NP_003366
RefSeq Peptide - NP_001171712
RefSeq Peptide - NP_001171752
RefSeq Peptide - NP_001311016
RefSeq Peptide - NP_001311017
RefSeq Peptide - NP_001311018
RefSeq Peptide - NP_001311019
swissprot - Q5JSD1
swissprot - Q5JSD2
swissprot - A2A3S1
swissprot - A0A0A0MR02
swissprot - A0A024QZT0
swissprot - P45880
Ensembl - ENSG00000165637
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vdac2ENSDARG00000013623Danio rerio
 VDAC2ENSGALG00000005002Gallus gallus
 Vdac2ENSMUSG00000021771Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
VDAC1 / P21796 / voltage dependent anion channel 1ENSG0000021358568
VDAC3 / Q9Y277 / voltage dependent anion channel 3ENSG0000007866867


Protein motifs (from Interpro)
Interpro ID Name
 IPR001925  Porin, eukaryotic type
 IPR027246  Eukaryotic porin/Tom40
 IPR030277  Voltage-dependent anion-selective channel protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006820 anion transport IDA
 biological_processGO:0007339 binding of sperm to zona pellucida IMP
 biological_processGO:0015698 inorganic anion transport IEA
 biological_processGO:0032272 negative regulation of protein polymerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0098656 anion transmembrane transport IEA
 biological_processGO:2001243 negative regulation of intrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0001669 acrosomal vesicle IDA
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042645 mitochondrial nucleoid IDA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0046930 pore complex IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008308 voltage-gated anion channel activity IDA
 molecular_functionGO:0015288 porin activity IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases
Mitochondrial calcium ion transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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