ENSG00000213585


Homo sapiens

Features
Gene ID: ENSG00000213585
  
Biological name :VDAC1
  
Synonyms : P21796 / VDAC1 / voltage dependent anion channel 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q31.1
Gene start: 133971915
Gene end: 134005133
  
Corresponding Affymetrix probe sets: 212038_s_at (Human Genome U133 Plus 2.0 Array)   217140_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000378484
Ensembl peptide - ENSP00000390129
Ensembl peptide - ENSP00000378487
Ensembl peptide - ENSP00000265333
NCBI entrez gene - 7416     See in Manteia.
OMIM - 604492
RefSeq - XM_017009821
RefSeq - XM_017009822
RefSeq - XM_017009823
RefSeq - NM_003374
RefSeq - XM_005272075
RefSeq Peptide - NP_003365
swissprot - P21796
swissprot - A0A1L1UHR1
swissprot - C9JI87
Ensembl - ENSG00000213585
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vdac1ENSDARG00000045132Danio rerio
 VDAC1ENSGALG00000006503Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
VDAC2 / P45880 / voltage dependent anion channel 2ENSG0000016563775
VDAC3 / Q9Y277 / voltage dependent anion channel 3ENSG0000007866867


Protein motifs (from Interpro)
Interpro ID Name
 IPR001925  Porin, eukaryotic type
 IPR027246  Eukaryotic porin/Tom40
 IPR030270  Voltage-dependent anion-selective channel protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006820 anion transport IEA
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0015698 inorganic anion transport IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0030855 epithelial cell differentiation IEP
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0098656 anion transmembrane transport IEA
 biological_processGO:1903146 regulation of autophagy of mitochondrion NAS
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005757 mitochondrial permeability transition pore complex IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane ISS
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042645 mitochondrial nucleoid IDA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0046930 pore complex TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008308 voltage-gated anion channel activity IEA
 molecular_functionGO:0015288 porin activity IEA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0044325 ion channel binding IPI


Pathways (from Reactome)
Pathway description
Mitochondrial protein import
Pink/Parkin Mediated Mitophagy
Ub-specific processing proteases
Pyruvate metabolism
Mitochondrial calcium ion transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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