ENSG00000166090


Homo sapiens

Features
Gene ID: ENSG00000166090
  
Biological name :IL25
  
Synonyms : IL25 / interleukin 25 / Q9H293
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q11.2
Gene start: 23372809
Gene end: 23376403
  
Corresponding Affymetrix probe sets: 220971_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000328111
Ensembl peptide - ENSP00000380417
NCBI entrez gene - 64806     See in Manteia.
OMIM - 605658
RefSeq - NM_022789
RefSeq - NM_172314
RefSeq Peptide - NP_073626
RefSeq Peptide - NP_758525
swissprot - Q9H293
Ensembl - ENSG00000166090
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Il25ENSMUSG00000040770Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IL17C / Q9P0M4 / interleukin 17CENSG0000012439127


Protein motifs (from Interpro)
Interpro ID Name
 IPR010345  Interleukin-17 family
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002437 inflammatory response to antigenic stimulus IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0009620 response to fungus IEA
 biological_processGO:0009624 response to nematode IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030222 eosinophil differentiation IEA
 biological_processGO:0032616 interleukin-13 production IEA
 biological_processGO:0032634 interleukin-5 production IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0097400 interleukin-17-mediated signaling pathway TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0030380 interleukin-17E receptor binding TAS


Pathways (from Reactome)
Pathway description
Interleukin-17 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000056736 IL17RB / Q9NRM6 / interleukin 17 receptor B  / complex
 ENSG00000177663 IL17RA / Q96F46 / interleukin 17 receptor A  / complex
 ENSG00000166090 IL25 / Q9H293 / interleukin 25  / complex






 

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contact: otassy@igbmc.fr