ENSG00000166136


Homo sapiens

Features
Gene ID: ENSG00000166136
  
Biological name :NDUFB8
  
Synonyms : NADH:ubiquinone oxidoreductase subunit B8 / NDUFB8 / O95169
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q24.31
Gene start: 100523740
Gene end: 100530000
  
Corresponding Affymetrix probe sets: 201226_at (Human Genome U133 Plus 2.0 Array)   201227_s_at (Human Genome U133 Plus 2.0 Array)   214241_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000434072
Ensembl peptide - ENSP00000299166
Ensembl peptide - ENSP00000359344
Ensembl peptide - ENSP00000359346
NCBI entrez gene - 4714     See in Manteia.
OMIM - 602140
RefSeq - NM_001284367
RefSeq - NM_001284368
RefSeq - NM_005004
RefSeq Peptide - NP_001271296
RefSeq Peptide - NP_001271297
RefSeq Peptide - NP_004995
swissprot - O95169
swissprot - E9PIZ8
Ensembl - ENSG00000166136
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ndufb8ENSDARG00000010113Danio rerio
 NDUFB8ENSGALG00000005704Gallus gallus
 Ndufb8ENSMUSG00000025204Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AL133352.1ENSG0000025533986


Protein motifs (from Interpro)
Interpro ID Name
 IPR008699  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8
 IPR016551  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006120 mitochondrial electron transport, NADH to ubiquinone TAS
 biological_processGO:0006626 protein targeting to mitochondrion TAS
 biological_processGO:0032981 mitochondrial respiratory chain complex I assembly TAS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane TAS
 cellular_componentGO:0005747 mitochondrial respiratory chain complex I IMP
 cellular_componentGO:0005759 mitochondrial matrix TAS
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070469 respiratory chain IEA
 molecular_functionGO:0003954 NADH dehydrogenase activity IEA
 molecular_functionGO:0008137 NADH dehydrogenase (ubiquinone) activity IEA


Pathways (from Reactome)
Pathway description
Mitochondrial protein import
Respiratory electron transport
Complex I biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000105819 PMPCB / O75439 / peptidase, mitochondrial processing beta subunit  / reaction






 

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