ENSMUSG00000025204


Mus musculus

Features
Gene ID: ENSMUSG00000025204
  
Biological name :Ndufb8
  
Synonyms : Mus musculus NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8 (Ndufb8), transcript variant 2, mRNA. / Ndufb8 / Q9D6J5
  
Possible biological names infered from orthology : AL133352.1 / NADH:ubiquinone oxidoreductase subunit B8 / O95169
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: C3
Gene start: 44548572
Gene end: 44555440
  
Corresponding Affymetrix probe sets: 10468016 (MoGene1.0st)   1448198_a_at (Mouse Genome 430 2.0 Array)   1458404_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026222
Ensembl peptide - ENSMUSP00000130918
Ensembl peptide - ENSMUSP00000132421
Ensembl peptide - ENSMUSP00000132740
Ensembl peptide - ENSMUSP00000128192
NCBI entrez gene - 67264     See in Manteia.
MGI - MGI:1914514
RefSeq - XM_006527292
RefSeq - NM_001347447
RefSeq - NM_026061
RefSeq Peptide - NP_080337
RefSeq Peptide - NP_001334376
swissprot - E9Q9J5
swissprot - Q9D6J5
swissprot - Q3V406
swissprot - F6VCY0
swissprot - E9PY23
Ensembl - ENSMUSG00000025204
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ndufb8ENSDARG00000010113Danio rerio
 NDUFB8ENSGALG00000005704Gallus gallus
 AL133352.1ENSG00000255339Homo sapiens
 NDUFB8ENSG00000166136Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm20538ENSMUSG0000009147126


Protein motifs (from Interpro)
Interpro ID Name
 IPR008699  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8
 IPR016551  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006120 mitochondrial electron transport, NADH to ubiquinone IEA
 biological_processGO:0032981 mitochondrial respiratory chain complex I assembly ISS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 cellular_componentGO:0005747 mitochondrial respiratory chain complex I ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070469 respiratory chain IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003954 NADH dehydrogenase activity IEA
 molecular_functionGO:0008137 NADH dehydrogenase (ubiquinone) activity IEA


Pathways (from Reactome)
Pathway description
Mitochondrial protein import
Respiratory electron transport
Complex I biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005015 increased T cell number "greater than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

 MP:0010168 increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number "a greater number of the CD4-positive, CD25-positive T cell subset which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release" [ISBN:0781735149]
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Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Nampttm1.1(KOMP)Vlcg/Nampttm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Nampttm1.1(KOMP)Vlcg/Ucd

 MP:0012764 increased alpha-beta T cell number "greater number of T cells that expresses an alpha-beta T cell receptor complex" [CL:0000789]
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Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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