ENSG00000166166


Homo sapiens

Features
Gene ID: ENSG00000166166
  
Biological name :TRMT61A
  
Synonyms : Q96FX7 / TRMT61A / tRNA methyltransferase 61A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q32.33
Gene start: 103529184
Gene end: 103537073
  
Corresponding Affymetrix probe sets: 1554317_s_at (Human Genome U133 Plus 2.0 Array)   221907_at (Human Genome U133 Plus 2.0 Array)   52741_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000374399
Ensembl peptide - ENSP00000299202
NCBI entrez gene - 115708     See in Manteia.
RefSeq - NM_152307
RefSeq Peptide - NP_689520
swissprot - Q96FX7
swissprot - A0A024R6Q2
swissprot - H0Y2Q1
Ensembl - ENSG00000166166
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trmt61aENSDARG00000008480Danio rerio
 TRMT61AENSGALG00000011522Gallus gallus
 Q80XC2ENSMUSG00000060950Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR014816  tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006400 tRNA modification TAS
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0030488 tRNA methylation IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0080009 mRNA methylation IDA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0031515 tRNA (m1A) methyltransferase complex IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016429 tRNA (adenine-N1-)-methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0061953 mRNA (adenine-N1-)-methyltransferase activity IDA


Pathways (from Reactome)
Pathway description
tRNA modification in the nucleus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000089195 TRMT6 / Q9UJA5 / tRNA methyltransferase 6  / complex
 ENSG00000166166 Q96FX7 / TRMT61A / tRNA methyltransferase 61A  / complex






 

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contact: otassy@igbmc.fr