ENSG00000166211


Homo sapiens

Features
Gene ID: ENSG00000166211
  
Biological name :SPIC
  
Synonyms : Q8N5J4 / SPIC / Spi-C transcription factor
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q23.2
Gene start: 101475421
Gene end: 101486997
  
Corresponding Affymetrix probe sets: 1553851_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000448580
NCBI entrez gene - 121599     See in Manteia.
OMIM - 612568
RefSeq - XM_006719239
RefSeq - NM_152323
RefSeq - XM_005268646
RefSeq Peptide - NP_689536
swissprot - Q8N5J4
Ensembl - ENSG00000166211
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spicENSDARG00000012435Danio rerio
 SPICENSGALG00000027209Gallus gallus
 SpicENSMUSG00000004359Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SPIB / Q01892 / Spi-B transcription factorENSG0000026940428
AC020909.1ENSG0000014253928
SPI1 / P17947 / Spi-1 proto-oncogeneENSG0000006633627


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001824 blastocyst development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
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