ENSG00000166428


Homo sapiens

Features
Gene ID: ENSG00000166428
  
Biological name :PLD4
  
Synonyms : phospholipase D family member 4 / PLD4 / Q96BZ4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q32.33
Gene start: 104924816
Gene end: 104937790
  
Corresponding Affymetrix probe sets: 1566433_at (Human Genome U133 Plus 2.0 Array)   235802_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000376372
Ensembl peptide - ENSP00000438677
Ensembl peptide - ENSP00000451278
Ensembl peptide - ENSP00000451636
NCBI entrez gene - 122618     See in Manteia.
RefSeq - XM_017020965
RefSeq - NM_001308174
RefSeq - NM_138790
RefSeq - XM_011536411
RefSeq Peptide - NP_001295103
RefSeq Peptide - NP_620145
swissprot - F5H2B5
swissprot - G3V3J8
swissprot - G3V472
swissprot - Q96BZ4
Ensembl - ENSG00000166428
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLD4ENSGALG00000011646Gallus gallus
 Pld4ENSMUSG00000052160Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PLD3 / Q8IV08 / phospholipase D family member 3ENSG0000010522341
PLD5 / Q8N7P1 / phospholipase D family member 5ENSG0000018028729


Protein motifs (from Interpro)
Interpro ID Name
 IPR001736  Phospholipase D/Transphosphatidylase
 IPR025202  Phospholipase D-like domain
 IPR032803  PLD-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006909 phagocytosis IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0043647 inositol phosphate metabolic process TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032588 trans-Golgi network membrane IEA
 cellular_componentGO:0045335 phagocytic vesicle IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004435 phosphatidylinositol phospholipase C activity TAS
 molecular_functionGO:0004630 phospholipase D activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PG
Synthesis of IP3 and IP4 in the cytosol
Role of phospholipids in phagocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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